Literature DB >> 31048187

Multicenter randomized controlled trial comparing the effectiveness and safety of hydrocellular and hydrocolloid dressings for treatment of category II pressure ulcers in patients at primary and long-term care institutions.

Angélica Miguélez Chamorro1, M Clara Vidal Thomas2, Aina Soler Mieras3, Alfonso Leiva3, Martí Pons Martínez4, M Maria Soledad Hernández Yeste5.   

Abstract

BACKGROUND: Pressure ulcers are a major burden to patients because they affect health, well-being, and health-related quality of life. Thus, prevention and early treatment of pressure ulcers is a major challenge for health care professionals.
OBJECTIVE: To compare the efficacy of hydrocellular and hydrocolloid dressings after 8 weeks of treatment of category II pressure ulcers.
DESIGN: A prospective multicenter clinical trial with blinded outcome assessors. PARTICIPANTS AND SETTINGS: Adult patients with category II pressure ulcers from primary and long-term care institutions on Majorca island.
METHODS: Category II ulcers were treated with ALLEVYN Adhesive® dressings or VARIHESIVE® GEL CONTROL dressings, with the primary outcome being healing of the ulcers in 8 weeks. Blinded confirmation of ulcer healing was performed by a treatment-group assessment committee. Estimates of cumulative survival probabilities were determined using the Kaplan-Meier method and analyses of effectiveness were performed using the chi-squared test.
RESULTS: A total of 169 patients with pressure ulcers were enrolled, 84 of whom received hydrocellular dressings and 85 of whom received hydrocolloid dressings. A total of 58% were women and 56% were from primary care institutions. The hydrocellular dressing group had a higher percentage of healed pressure ulcers at 8 weeks (90.7% vs. 77.1%, p = 0.039) and a shorter average healing time (3 weeks vs. 4 weeks, p = 0.015). Analysis of safety outcomes at 8 weeks indicated that the hydrocellular dressing group had a smaller proportion of ulcers that were unhealed (3.9% vs. 7.1%) and a smaller proportion of ulcers that progressed to a higher category or infection (5.3% vs. 15.7%), although these differences were not statistically significant.
CONCLUSIONS: This study of patients with category II pressure ulcers indicated that hydrocellular dressings were superior to hydrocolloid dressings in terms of healing at 8 weeks and time required for healing, although these two dressings had similar safety profiles.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Hydrocellular dressing; Hydrocolloid dressing; Pressure ulcer; Randomized clinical trial

Mesh:

Substances:

Year:  2019        PMID: 31048187     DOI: 10.1016/j.ijnurstu.2019.03.021

Source DB:  PubMed          Journal:  Int J Nurs Stud        ISSN: 0020-7489            Impact factor:   5.837


  4 in total

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Authors:  Alexandra Elena Stoica; Cristina Chircov; Alexandru Mihai Grumezescu
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3.  Effectiveness of Hydrocolloid Dressings for Treating Pressure Ulcers in Adult Patients: A Systematic Review and Meta-Analysis.

Authors:  Magdalena Sylwia Kamińska; Anna Maria Cybulska; Karolina Skonieczna-Żydecka; Katarzyna Augustyniuk; Elżbieta Grochans; Beata Karakiewicz
Journal:  Int J Environ Res Public Health       Date:  2020-10-27       Impact factor: 3.390

4.  Clinical and Economic Impact of Wound Care Using a Polyurethane Foam Multilayer Dressing.

Authors:  Verónica Tiscar-González; Maria José Menor-Rodríguez; Carlos Rabadán-Sainz; Mercedes Fraile-Bravo; Tim Styche; Francisco José Valenzuela-Ocaña; Leticia Muñoz-García
Journal:  Adv Skin Wound Care       Date:  2021-01       Impact factor: 2.373

  4 in total

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