Literature DB >> 31044479

Obstetrical prognosis of patients who underwent vaginal radical trachelectomy during pregnancy.

Mina Umemoto1, Shinichi Ishioka1, Yuko Mizugaki1, Yuya Fujibe1, Tasuku Mariya1, Akari Kawamata1, Masahito Mizuuchi1, Miyuki Morishita1, Tsuyoshi Baba1, Tsuyoshi Saito1.   

Abstract

AIM: Radical trachelectomy (RT) with pelvic lymphadenectomy has become an option for young patients with early invasive uterine cervical cancer who decide to maintain their fertility. However, this operative method entails a high risk for the following pregnancy due to its radicality. Therefore, RT for pregnant patients can be a challenge both for gynecologic oncologists and obstetricians.
METHODS: We have performed vaginal RT for five pregnant patients with uterine cervical cancer stage 1B1 according to the method of Dargent et al. The operations were performed between 16 and 26 weeks of pregnancy, and the patients were followed up carefully according to the follow-up methods we reported previously.
RESULTS: Vaginal RT was performed for five patients without any troubles. Four of the patients continued their pregnancies until almost 34 weeks or longer under our previously published follow-up schedule. The pregnancy of one patient was terminated at 26 weeks due to recurrence of the cancer.
CONCLUSION: Expansion of vaginal RT for pregnant patients with uterine cervical cancer could be a practical option for pregnant patients with early invasive uterine cervical cancer.
© 2019 Japan Society of Obstetrics and Gynecology.

Entities:  

Keywords:  cervical cancer; fertility; pregnancy; trachelectomy

Mesh:

Year:  2019        PMID: 31044479     DOI: 10.1111/jog.13964

Source DB:  PubMed          Journal:  J Obstet Gynaecol Res        ISSN: 1341-8076            Impact factor:   1.730


  2 in total

1.  Pregnancies after vaginal radical trachelectomy (RT) in patients with early invasive uterine cervical cancer: results from a single institute.

Authors:  Shota Shinkai; Shinichi Ishioka; Tasuku Mariya; Yuya Fujibe; Miseon Kim; Masayuki Someya; Tsuyoshi Saito
Journal:  BMC Pregnancy Childbirth       Date:  2020-04-25       Impact factor: 3.007

2.  Neoadjuvant chemotherapy for locally invasive cervical cancer in pregnancy: two case reports.

Authors:  Ming-Zhu Li; Yun Zhao; Yu-Ligh Liou; Xiao-Ping Li; Xiao-Hong Zhang; Yue Wang; Zhi-Qi Wang; Xiao-Lian Zhu; Jian-Liu Wang; Li-Hui Wei
Journal:  Transl Cancer Res       Date:  2019-08       Impact factor: 1.241

  2 in total

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