Literature DB >> 31044453

Methadone Disposition: Implementing Lessons Learned.

Evan D Kharasch1, David J Greenblatt2.   

Abstract

Entities:  

Keywords:  CYP2B6; clinical pharmacology (CPH); drug abuse; drug-drug interactions; methadone; pharmacokinetics and drug metabolism

Year:  2019        PMID： 31044453      PMCID： PMC6606361          DOI： 10.1002/jcph.1427

Source DB:  PubMed          Journal:  J Clin Pharmacol        ISSN： 0091-2700            Impact factor:   3.126


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  36 in total

1.  Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation.

Authors:  Miia Turpeinen; Ari Tolonen; Jouko Uusitalo; Jorma Jalonen; Olavi Pelkonen; Kari Laine
Journal:  Clin Pharmacol Ther       Date:  2005-06       Impact factor: 6.875

2.  CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.

Authors:  L M Hesse; K Venkatakrishnan; M H Court; L L von Moltke; S X Duan; R I Shader; D J Greenblatt
Journal:  Drug Metab Dispos       Date:  2000-10       Impact factor: 3.922

3.  Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.

Authors:  S R Faucette; R L Hawke; E L Lecluyse; S S Shord; B Yan; R M Laethem; C M Lindley
Journal:  Drug Metab Dispos       Date:  2000-10       Impact factor: 3.922

4.  Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: potential drug interactions with bupropion.

Authors:  L M Hesse; L L von Moltke; R I Shader; D J Greenblatt
Journal:  Drug Metab Dispos       Date:  2001-02       Impact factor: 3.922

5.  Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment.

Authors:  Séverine Crettol; Jean-Jacques Déglon; Jacques Besson; Marina Croquette-Krokkar; Isabelle Gothuey; Robert Hämmig; Martine Monnat; Hardy Hüttemann; Pierre Baumann; Chin B Eap
Journal:  Clin Pharmacol Ther       Date:  2005-12       Impact factor: 6.875

6.  Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.

Authors:  B Goodwin; L B Moore; C M Stoltz; D D McKee; S A Kliewer
Journal:  Mol Pharmacol       Date:  2001-09       Impact factor: 4.436

7.  Human CYP2B6: expression, inducibility and catalytic activities.

Authors:  L Gervot; B Rochat; J C Gautier; F Bohnenstengel; H Kroemer; V de Berardinis; H Martin; P Beaune; I de Waziers
Journal:  Pharmacogenetics       Date:  1999-06

8.  Potent mechanism-based inhibition of human CYP2B6 by clopidogrel and ticlopidine.

Authors:  Tanja Richter; Thomas E Mürdter; Georg Heinkele; Jürgen Pleiss; Stephan Tatzel; Matthias Schwab; Michel Eichelbaum; Ulrich M Zanger
Journal:  J Pharmacol Exp Ther       Date:  2003-10-16       Impact factor: 4.030

9.  Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.

Authors:  Evan D Kharasch; Christine Hoffer; Dale Whittington; Pamela Sheffels
Journal:  Clin Pharmacol Ther       Date:  2004-09       Impact factor: 6.875

10.  Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.

Authors:  John G Gerber; Robert J Rhodes; Joseph Gal
Journal:  Chirality       Date:  2004-01       Impact factor: 2.437
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  5 in total

Review 1.  Methadone for Pain Management: A Pharmacotherapeutic Review.

Authors:  Denise Kreutzwiser; Qutaiba A Tawfic
Journal:  CNS Drugs       Date:  2020-08       Impact factor: 5.749

2.  Utilizing Pediatric Physiologically Based Pharmacokinetic Models to Examine Factors That Contribute to Methadone Pharmacokinetic Variability in Neonatal Abstinence Syndrome Patients.

Authors:  Brooks T McPhail; Chie Emoto; Tsuyoshi Fukuda; Dawn Butler; Jason R Wiles; Henry Akinbi; Alexander A Vinks
Journal:  J Clin Pharmacol       Date:  2019-12-09       Impact factor: 3.126

3.  Toward precision prescribing for methadone: Determinants of methadone deposition.

Authors:  Andrew H Talal; Yuxin Ding; Charles S Venuto; Lindsay M Chakan; Anthony McLeod; Arpan Dharia; Gene D Morse; Lawrence S Brown; Marianthi Markatou; Evan D Kharasch
Journal:  PLoS One       Date:  2020-04-17       Impact factor: 3.240

Review 4.  CYP2B6 Functional Variability in Drug Metabolism and Exposure Across Populations-Implication for Drug Safety, Dosing, and Individualized Therapy.

Authors:  Immaculate M Langmia; Katja S Just; Sabrina Yamoune; Jürgen Brockmöller; Collen Masimirembwa; Julia C Stingl
Journal:  Front Genet       Date:  2021-07-12       Impact factor: 4.599

Review 5.  Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments.

Authors:  Fei Tang; Chee M Ng; Henrietta S Bada; Markos Leggas
Journal:  Clin Transl Sci       Date:  2021-05-01       Impact factor: 4.689
  5 in total

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