Literature DB >> 31043737

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.

Jiyeon Kim1, Zeping Hu1, Ling Cai1, Kailong Li1, Eunhee Choi2, Brandon Faubert1, Divya Bezwada1, Jaime Rodriguez-Canales3, Pamela Villalobos3, Yu-Fen Lin4, Min Ni1, Kenneth E Huffman5, Luc Girard5, Lauren A Byers6, Keziban Unsal-Kacmaz7, Christopher G Peña8,9, John V Heymach6, Els Wauters10, Johan Vansteenkiste10, Diego H Castrillon8, Benjamin P C Chen4, Ignacio Wistuba3, Diether Lambrechts11,12, Jian Xu1, John D Minna5, Ralph J DeBerardinis13,14,15.   

Abstract

Further analysis has revealed that the signal reported in Extended Data Fig. 1c of this Letter is attributed to phosphorylethanolamine, not carbamoyl phosphate. A newly developed derivatization method revealed that the level of carbamoyl phosphate in these NSCLC extracts is below the detection threshold of approximately 10 nanomoles. These findings do not alter the overall conclusions of the Letter; see associated Amendment for full details. The Letter has not been corrected online.

Entities:  

Year:  2019        PMID: 31043737     DOI: 10.1038/s41586-019-1133-3

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  1 in total

1.  Studies on the biosynthesis of carbamylaspartic acid.

Authors:  J M LOWENSTEIN; P P COHEN
Journal:  J Biol Chem       Date:  1956-05       Impact factor: 5.157

  1 in total
  2 in total

1.  Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado.

Authors:  Ana Galan-Cobo; Christine M Stellrecht; Emrullah Yilmaz; Chao Yang; Yu Qian; Xiao Qu; Ishita Akhter; Mary L Ayres; Youhong Fan; Pan Tong; Lixia Diao; Jie Ding; Uma Giri; Jayanthi Gudikote; Monique Nilsson; William G Wierda; Jing Wang; Ferdinandos Skoulidis; John D Minna; Varsha Gandhi; John V Heymach
Journal:  Mol Cancer Res       Date:  2021-10-15       Impact factor: 6.333

2.  Evolutionary selection identifies critical immune-relevant genes in lung cancer subtypes.

Authors:  Kimberly A Luddy; Jamie K Teer; Audrey Freischel; Cliona O'Farrelly; Robert Gatenby
Journal:  Front Genet       Date:  2022-08-24       Impact factor: 4.772

  2 in total

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