Literature DB >> 3104093

Competition between tetracycline and tRNA at both P and A sites of the ribosome of Escherichia coli.

B Epe, P Woolley, H Hornig.   

Abstract

Fluorescence anisotropy studies performed on 6-demethylchlortetracycline, binding to the ribosome of E. coli in competition with tRNA at the P site or at both P and A sites, have provided a quantitative assessment in situ of the interaction of this antibiotic with the A site and have demonstrated that there is also an interaction between tetracycline and the P site.

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Year:  1987        PMID: 3104093     DOI: 10.1016/0014-5793(87)81539-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  9 in total

1.  Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR.

Authors:  Dorith Wunnicke; Denise Strohbach; Julia E Weigand; Bettina Appel; Emiliano Feresin; Beatrix Suess; Sabine Müller; Heinz-Jürgen Steinhoff
Journal:  RNA       Date:  2010-11-19       Impact factor: 4.942

2.  Interaction of tetracycline with RNA: photoincorporation into ribosomal RNA of Escherichia coli.

Authors:  R Oehler; N Polacek; G Steiner; A Barta
Journal:  Nucleic Acids Res       Date:  1997-03-15       Impact factor: 16.971

3.  Fluorimetric distance determination by resonance energy transfer. Ribosome-bound transfer RNA.

Authors:  K Friedrich; P Woolley; K G Steinhäuser
Journal:  Eur Biophys J       Date:  1988       Impact factor: 1.733

4.  tRNA modification activity is necessary for Tet(M)-mediated tetracycline resistance.

Authors:  V Burdett
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490

5.  Binding interaction between Tet(M) and the ribosome: requirements for binding.

Authors:  K A Dantley; H K Dannelly; V Burdett
Journal:  J Bacteriol       Date:  1998-08       Impact factor: 3.490

Review 6.  Bacterial resistance to tetracycline: mechanisms, transfer, and clinical significance.

Authors:  B S Speer; N B Shoemaker; A A Salyers
Journal:  Clin Microbiol Rev       Date:  1992-10       Impact factor: 26.132

7.  Mechanism of tetracycline resistance by ribosomal protection protein Tet(O).

Authors:  Wen Li; Gemma C Atkinson; Nehal S Thakor; Ular Allas; Chuao-chao Lu; Kwok-Yan Chan; Tanel Tenson; Klaus Schulten; Kevin S Wilson; Vasili Hauryliuk; Joachim Frank
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

Review 8.  Antibiotic drugs targeting bacterial RNAs.

Authors:  Weiling Hong; Jie Zeng; Jianping Xie
Journal:  Acta Pharm Sin B       Date:  2014-07-31       Impact factor: 11.413

Review 9.  Resistance mechanisms in Campylobacter jejuni.

Authors:  Nicole M Iovine
Journal:  Virulence       Date:  2013-02-13       Impact factor: 5.882

  9 in total

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