Literature DB >> 3104028

Selective radiolabelling and identification of a strong nucleosome binding site on the globular domain of histone H5.

J O Thomas, C M Wilson.   

Abstract

We describe a chemical investigation of the nucleosome binding site(s) on histone H5. Selective radiolabelling by reductive methylation has led to the identification of lysine residues in H5 that are protected by its association with chromatin. The most strongly protected lysine is Lys-85 which occurs in the globular domain, in a region that is highly conserved between H5 and H1, and in H1 variants, and which probably constitutes a strong binding site for DNA where it enters and leaves the nucleosome. Lysines in the amino-terminal and lysine-rich carboxy-terminal tails are only weakly protected against chemical modification, suggesting a different mode of interaction with DNA.

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Year:  1986        PMID： 3104028      PMCID： PMC1167390          DOI： 10.1002/j.1460-2075.1986.tb04679.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  35 in total

1.  Lysine-containing DNA-binding regions on the surface of the histone octamer in the nucleosome core particle.

Authors:  S F Lambert; J O Thomas
Journal:  Eur J Biochem       Date:  1986-10-01

2.  The stoichiometry of polypeptide chains in the pyruvate dehydrogenase multienzyme complex of E. coli determined by a simple novel method.

Authors:  D L Bates; R A Harrison; R N Perham
Journal:  FEBS Lett       Date:  1975-12-15       Impact factor: 4.124

3.  Differential distribution of lysine and arginine residues in the closely related histones H1 and H5. Analysis of a human H1 gene.

Authors:  D Doenecke; R Tönjes
Journal:  J Mol Biol       Date:  1986-02-05       Impact factor: 5.469

4.  Effect of N-methylation and chain length on kinetic constants of trypsin substrates. Epsilon-N-methyllysine and homolysine derivatives as substrates.

Authors:  J H Seely; N L Benoiton
Journal:  Can J Biochem       Date:  1970-10

5.  Studies on histones. 7. Preparative methods for histone fractions from calf thymus.

Authors:  E W Johns
Journal:  Biochem J       Date:  1964-07       Impact factor: 3.857

Review 6.  Protein-DNA recognition.

Authors:  C O Pabo; R T Sauer
Journal:  Annu Rev Biochem       Date:  1984       Impact factor: 23.643

7.  Structure of the nucleosome core particle at 7 A resolution.

Authors:  T J Richmond; J T Finch; B Rushton; D Rhodes; A Klug
Journal:  Nature       Date:  1984 Oct 11-17       Impact factor: 49.962

8.  Primary structure of the two variants of a sperm-specific histone H1 from the annelid Platynereis dumerilii.

Authors:  D Kmiecik; D Sellos; D Belaïche; P Sautiere
Journal:  Eur J Biochem       Date:  1985-07-15

9.  Transition from noncooperative to cooperative and selective binding of histone H1 to DNA.

Authors:  M Renz; L A Day
Journal:  Biochemistry       Date:  1976-07-27       Impact factor: 3.162

10.  Salt-dependent co-operative interaction of histone H1 with linear DNA.

Authors:  D J Clark; J O Thomas
Journal:  J Mol Biol       Date:  1986-02-20       Impact factor: 5.469
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  13 in total

1.  The linker histone homolog Hho1p from Saccharomyces cerevisiae represents a winged helix-turn-helix fold as determined by NMR spectroscopy.

Authors:  Katsuki Ono; Osamu Kusano; Sakurako Shimotakahara; Mitsuhiro Shimizu; Toshimasa Yamazaki; Heisaburo Shindo
Journal:  Nucleic Acids Res       Date:  2003-12-15       Impact factor: 16.971

2.  Molecular modeling of the chromatosome particle.

Authors:  M M Srinivas Bharath; Nagasuma R Chandra; M R S Rao
Journal:  Nucleic Acids Res       Date:  2003-07-15       Impact factor: 16.971

3.  Structure analysis of purified histone H5 and of H5 in nuclei by limited proteolysis.

Authors:  M Hallupp; F Buck; W H Strätling
Journal:  Biochem J       Date:  1992-03-01       Impact factor: 3.857

4.  Complex of linker histone H5 with the nucleosome and its implications for chromatin packing.

Authors:  Li Fan; Victoria A Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  2006-05-22       Impact factor: 11.205

5.  Cooperative binding of the globular domains of histones H1 and H5 to DNA.

Authors:  J O Thomas; C Rees; J T Finch
Journal:  Nucleic Acids Res       Date:  1992-01-25       Impact factor: 16.971

6.  Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.

Authors:  Jan Bednar; Isabel Garcia-Saez; Ramachandran Boopathi; Amber R Cutter; Gabor Papai; Anna Reymer; Sajad H Syed; Imtiaz Nisar Lone; Ognyan Tonchev; Corinne Crucifix; Hervé Menoni; Christophe Papin; Dimitrios A Skoufias; Hitoshi Kurumizaka; Richard Lavery; Ali Hamiche; Jeffrey J Hayes; Patrick Schultz; Dimitar Angelov; Carlo Petosa; Stefan Dimitrov
Journal:  Mol Cell       Date:  2017-05-04       Impact factor: 17.970

7.  Identification of two DNA-binding sites on the globular domain of histone H5.

Authors:  F A Goytisolo; S E Gerchman; X Yu; C Rees; V Graziano; V Ramakrishnan; J O Thomas
Journal:  EMBO J       Date:  1996-07-01       Impact factor: 11.598

8.  Distribution of high mobility group proteins 1/2, E and 14/17 and linker histones H1 and H5 on transcribed and non-transcribed regions of chicken erythrocyte chromatin.

Authors:  Y V Postnikov; V V Shick; A V Belyavsky; K R Khrapko; K L Brodolin; T A Nikolskaya; A D Mirzabekov
Journal:  Nucleic Acids Res       Date:  1991-02-25       Impact factor: 16.971

9.  Predicting protein-DNA interactions by full search computational docking.

Authors:  Victoria A Roberts; Michael E Pique; Lynn F Ten Eyck; Sheng Li
Journal:  Proteins       Date:  2013-10-18

10.  Bands, interbands and puffs in native Drosophila polytene chromosomes are recognized by a monoclonal antibody to an epitope in the carboxy-terminal tail of histone H1.

Authors:  R J Hill; F Watt; C M Wilson; T Fifis; P A Underwood; G Tribbick; H M Geysen; J O Thomas
Journal:  Chromosoma       Date:  1989-12       Impact factor: 4.316
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