| Literature DB >> 31037368 |
Ling Tang1,2,3,4, Xiaoping Chen4, Xu Zhang1,2,3, Yeye Guo1,2,3, Juan Su1,2,3, Jianglin Zhang1,2,3, Cong Peng5,6,7,8, Xiang Chen9,10,11,12.
Abstract
Skin cancer can be classified as cutaneous malignant melanoma, basal cell carcinoma, and squamous cell carcinoma. Due to the high level of morbidity and mortality, skin cancer has become a global public health issue worldwide while the pathogenesis of skin cancer is still unclear. It is necessary to further identify the pathogenesis of skin cancer and find candidate targets to diagnose and treat skin cancer. A variety of factors are known to be associated with skin cancer including N-glycosylation, which partly explained the malignant behaviors of skin cancer. In this review, we retrieved databases such as PubMed and Web of Science to elucidate its relationship between glycosylation and skin cancer. We summarized some key glycosyltransferases and proteins during the process of N-glycosylation related to skin cancer, which was helpful to unmask the additional mechanism of skin cancer and find some novel targets of skin cancer.Entities:
Keywords: Glycosyltransferases; Melanoma; N-glycosylation; NMSC
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Year: 2019 PMID： 31037368 DOI： 10.1007/s12032-019-1270-4
Source DB: PubMed Journal: Med Oncol ISSN： 1357-0560 Impact factor: 3.064