Literature DB >> 31037230

Case-Control Research Study of Auto-Brewery Syndrome.

Barbara Jean Cordell1, Anup Kanodia2, Gregory K Miller3.   

Abstract

BACKGROUND: Auto-brewery syndrome (ABS), also known as Gut Fermentation Syndrome and Endogenous Ethanol Fermentation, is afflicting people worldwide, but little is known about ABS patients' demographics, health history, lifestyle factors, and diet.
METHOD: We conducted a broad-based case-control survey study on 52 patients known to have a diagnosis of ABS and their household members. The research compares the symptomatic group (N = 28) to the asymptomatic group (N = 18) regarding lifestyle and health, diet, and medical history.
RESULTS: With a response rate of 88% and using rank-sum tests, the data demonstrate that patients with ABS have significant differences compared to people without ABS in lower quality bowel movements (P = .048), more frequent bowel movements (P = .038), more reports of malodorous breath (P = .0001), and self-classify as having poorer health (P = .009). Furthermore, participants with ABS consume more water (P = .038), consume less tea and coffee (P = .033), eat fewer dairy products (P = .0185), eat less candy (P = .032), eat out less and rely on food prepared at home (P = .043), have more aversion to starch (P = .008), and have more food sensitivities (P = .043) than the group without ABS. The ABS group also reports more diarrhea (P = .048), higher amounts of yeast in their gastrointestinal tract (P = .015), and using acne medication for a longer time (P = .037) than the control group.
CONCLUSION: Patients with ABS have significant differences in their lifestyle and health, diet, and medical history compared to non-ABS participants and these differences warrant further research.

Entities:  

Keywords:  alcohol; auto-brewery syndrome; endogenous ethanol; gut fermentation; research; yeast overgrowth

Year:  2019        PMID: 31037230      PMCID: PMC6475837          DOI: 10.1177/2164956119837566

Source DB:  PubMed          Journal:  Glob Adv Health Med        ISSN: 2164-9561


  24 in total

1.  Auto-brewery syndrome in a child with short gut syndrome: case report and review of the literature.

Authors:  A Dahshan; K Donovan
Journal:  J Pediatr Gastroenterol Nutr       Date:  2001-08       Impact factor: 2.839

2.  The auto-brewery syndrome--the repeated attacks of alcoholic intoxication due to the overgrowth of Candida (albicans) in the gastrointestinal tract.

Authors:  H Kaji; Y Asanuma; H Ide; N Saito; M Hisamura; M Murao; T Yoshida; K Takahashi
Journal:  Mater Med Pol       Date:  1976

3.  Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome.

Authors:  C Chassard; M Dapoigny; K P Scott; L Crouzet; C Del'homme; P Marquet; J C Martin; G Pickering; D Ardid; A Eschalier; C Dubray; H J Flint; A Bernalier-Donadille
Journal:  Aliment Pharmacol Ther       Date:  2012-02-08       Impact factor: 8.171

4.  Endogenous ethanol fermentation in a child with short bowel syndrome.

Authors:  Evelyn Jansson-Nettelbladt; Staffan Meurling; Björn Petrini; Jan Sjölin
Journal:  Acta Paediatr       Date:  2006-04       Impact factor: 2.299

5.  Long-term ecological impacts of antibiotic administration on the human intestinal microbiota.

Authors:  Cecilia Jernberg; Sonja Löfmark; Charlotta Edlund; Janet K Jansson
Journal:  ISME J       Date:  2007-05       Impact factor: 10.302

6.  Small intestinal bacterial overgrowth in patients with irritable bowel syndrome.

Authors:  Iris Posserud; Per-Ove Stotzer; Einar S Björnsson; Hasse Abrahamsson; Magnus Simrén
Journal:  Gut       Date:  2006-12-05       Impact factor: 23.059

7.  Obesity and female gender increase breath ethanol concentration: potential implications for the pathogenesis of nonalcoholic steatohepatitis.

Authors:  S Nair; K Cope; T H Risby; A M Diehl; R H Terence
Journal:  Am J Gastroenterol       Date:  2001-04       Impact factor: 10.864

Review 8.  Fermentation potential of the gut microbiome: implications for energy homeostasis and weight management.

Authors:  Tulika Arora; Rajkumar Sharma
Journal:  Nutr Rev       Date:  2011-02       Impact factor: 7.110

Review 9.  The emerging world of the fungal microbiome.

Authors:  Gary B Huffnagle; Mairi C Noverr
Journal:  Trends Microbiol       Date:  2013-05-17       Impact factor: 17.079

10.  The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing.

Authors:  Les Dethlefsen; Sue Huse; Mitchell L Sogin; David A Relman
Journal:  PLoS Biol       Date:  2008-11-18       Impact factor: 8.029

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  5 in total

1.  Gut fermentation syndrome: A systematic review of case reports.

Authors:  Ahmed B Bayoumy; Chris J J Mulder; Jaap J Mol; Maarten E Tushuizen
Journal:  United European Gastroenterol J       Date:  2021-04-22       Impact factor: 4.623

2.  Auto-brewery syndrome caused by oral fungi and periodontal disease bacteria.

Authors:  Gaku Takahashi; Koichi Hoshikawa; Shigenori Kan; Rise Akimaru; Yoshiyuki Kodama; Toshiro Sato; Keisuke Kakisaka; Yuki Yamada
Journal:  Acute Med Surg       Date:  2021-05-03

Review 3.  Case Report: Diabetic urinary auto-brewery and review of literature.

Authors:  Abdulrahman A Alduraywish
Journal:  F1000Res       Date:  2021-05-20

4.  Factors in an Auto-Brewery Syndrome group compared to an American Gut Project group: a case-control study.

Authors:  Barbara Cordell; Anup Kanodia; Gregory K Miller
Journal:  F1000Res       Date:  2021-06-08

Review 5.  Alcoholic Liver Disease: Current Mechanistic Aspects with Focus on Their Clinical Relevance.

Authors:  Rolf Teschke
Journal:  Biomedicines       Date:  2019-09-05
  5 in total

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