Literature DB >> 31036986

Pharmacology for the Audiologist.

Tracy Offerdahl1, Vallabhi Mishra2.   

Abstract

The purpose of this article is to provide a brief introduction and review regarding basic principles of pharmacology, including terminology and colloquialisms, as well as pharmacokinetic and pharmacodynamic principles of ototoxic agents. As an audiology practitioner, it is more important than ever to have a working knowledge regarding the known and proposed mechanisms of action for drugs and chemicals with known ototoxicity potential. Additionally, this article provides a discussion regarding the biochemistry behind distribution, which is a major step in determining ototoxic potential of known and potential ototoxins.

Entities:  

Keywords:  ADMET; distribution; ototoxicity; pharmacodynamics; pharmacokinetics

Year:  2019        PMID： 31036986      PMCID： PMC6486359          DOI： 10.1055/s-0039-1684038

Source DB:  PubMed          Journal:  Semin Hear        ISSN： 0734-0451


  9 in total

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Journal:  Nat Biotechnol       Date:  2001-08       Impact factor: 54.908

Review 2.  The integration of pharmacokinetics and pharmacodynamics: understanding dose-response.

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Journal:  Annu Rev Pharmacol Toxicol       Date:  2004       Impact factor: 13.820

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Journal:  Volta Rev       Date:  2005

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Authors:  Stephan Schmidt; Daniel Gonzalez; Hartmut Derendorf
Journal:  J Pharm Sci       Date:  2010-03       Impact factor: 3.534

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Authors:  Richard Daneman
Journal:  Ann Neurol       Date:  2012-11       Impact factor: 10.422

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Authors:  Erin E Leary Swan; Mark J Mescher; William F Sewell; Sarah L Tao; Jeffrey T Borenstein
Journal:  Adv Drug Deliv Rev       Date:  2008-09-21       Impact factor: 15.470

8.  Adverse Drug Reactions Causing Admission to Medical Wards: A Cross-Sectional Survey at 4 Hospitals in South Africa.

Authors:  Johannes P Mouton; Christine Njuguna; Nicole Kramer; Annemie Stewart; Ushma Mehta; Marc Blockman; Melony Fortuin-De Smidt; Reneé De Waal; Andy G Parrish; Douglas P K Wilson; Ehimario U Igumbor; Getahun Aynalem; Mukesh Dheda; Gary Maartens; Karen Cohen
Journal:  Medicine (Baltimore)       Date:  2016-05       Impact factor: 1.889

9.  Drug-drug interactions with imatinib: An observational study.

Authors:  Isabelle Récoché; Vanessa Rousseau; Robert Bourrel; Maryse Lapeyre-Mestre; Leila Chebane; Fabien Despas; Jean-Louis Montastruc; Emmanuelle Bondon-Guitton
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889
  9 in total

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