Literature DB >> 3103695

Solubility properties of reduced and oxidized ascorbate as determinants of membrane permeation.

R C Rose.   

Abstract

The oil/water distribution coefficients of ascorbic acid and dehydro-L-ascorbic acid have been determined and compared with values for mannitol and lauric acid. In general, the relative degrees of hydrophobicity of the compounds evaluated are lauric acid much greater than mannitol approximately equal to dehydro-L-ascorbic acid greater than ascorbic acid. These findings and recent reports from transport studies do not support the concept that dehydro-L-ascorbic acid is very hydrophobic and crosses cell membranes rapidly by simple diffusion.

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Year:  1987        PMID: 3103695     DOI: 10.1016/0304-4165(87)90094-8

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  8 in total

1.  Photosensitizer binding to lipid bilayers as a precondition for the photoinactivation of membrane channels.

Authors:  T I Rokitskaya; M Block; Y N Antonenko; E A Kotova; P Pohl
Journal:  Biophys J       Date:  2000-05       Impact factor: 4.033

2.  Absorption of ascorbic acid and ascorbic sulfate and ascorbate metabolism in common carp (Cyprinus carpio L.).

Authors:  K Dabrowski
Journal:  J Comp Physiol B       Date:  1990       Impact factor: 2.200

3.  Ascorbate free-radical reduction by glyoxysomal membranes.

Authors:  M L Bowditch; R P Donaldson
Journal:  Plant Physiol       Date:  1990-10       Impact factor: 8.340

4.  Transport of Ascorbic and Dehydroascorbic Acids across Protoplast and Vacuole Membranes Isolated from Barley (Hordeum vulgare L. cv Gerbel) Leaves.

Authors:  AAF. Rautenkranz; L. Li; F. Machler; E. Martinoia; J. J. Oertli
Journal:  Plant Physiol       Date:  1994-09       Impact factor: 8.340

Review 5.  Transport of vitamin C in animal and human cells.

Authors:  H Goldenberg; E Schweinzer
Journal:  J Bioenerg Biomembr       Date:  1994-08       Impact factor: 2.945

6.  Intracellular ascorbic acid enhances the DNA single-strand breakage and toxicity induced by peroxynitrite in U937 cells.

Authors:  A Guidarelli; R De Sanctis; B Cellini; M Fiorani; M Dachà; O Cantoni
Journal:  Biochem J       Date:  2001-06-01       Impact factor: 3.857

Review 7.  Vitamin C and Cardiovascular Disease: An Update.

Authors:  Marco B Morelli; Jessica Gambardella; Vanessa Castellanos; Valentina Trimarco; Gaetano Santulli
Journal:  Antioxidants (Basel)       Date:  2020-12-03

Review 8.  Regulation of vitamin C homeostasis during deficiency.

Authors:  Maiken Lindblad; Pernille Tveden-Nyborg; Jens Lykkesfeldt
Journal:  Nutrients       Date:  2013-07-25       Impact factor: 5.717

  8 in total

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