Literature DB >> 31036734

Large paraspinal abscess as a complication of infliximab therapy in Crohn's disease.

Nishani Nithianandan1, Michael J Loftus2, Paul D R Johnson2,3, Patrick G P Charles1,2,3.   

Abstract

We report a 36-year-old man who developed a large epidural and paraspinal abscess as a complication of infliximab therapy being used for underlying Crohn's disease. Cultures of the collection grew methicillin-susceptible Staphylococcus aureus, and treatment consisted of abscess drainage, prolonged intravenous and oral flucloxacillin and temporary withholding of his infliximab. While infection-related complications are well described with infliximab therapy, this is the first description of a large paraspinal abscess with epidural extension. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  bone and joint infections; crohn’s disease; infection (neurology); infections

Mesh:

Substances:

Year:  2019        PMID: 31036734      PMCID: PMC6506107          DOI: 10.1136/bcr-2018-227665

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  18 in total

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Review 9.  ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Soluble immune effector molecules [I]: anti-tumor necrosis factor-α agents).

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