Literature DB >> 31036731

Thyroid detectives: on the trail of Munchausen's syndrome.

Partha Pratim Chakraborty1, Soumik Goswami2, Rana Bhattacharjee3, Subhankar Chowdhury3.   

Abstract

Thyrotoxicosis factitia, a disorder frequently seen in young or middle-aged women with psychological disorders, most commonly results from surreptitious ingestion of excess thyroid hormones. In most patients, diagnosis is relatively straightforward and depends on the demonstration of biochemical thyrotoxicosis, suppressed endogenous thyroid function and absence of clinical features of underlying thyroid disease. However, at times, confounding factors can make the diagnosis particularly challenging and necessitate the investigating physician to don the detective's cap to get to the root of the problem. We discuss a patient whose diagnosis was reached with ingenuity after considerable effort from four endocrinologists having a total experience of 37 years in their field. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  endocrine system; general practice / family medicine; thyroid disease

Mesh:

Year:  2019        PMID: 31036731      PMCID: PMC6506104          DOI: 10.1136/bcr-2018-226087

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

Review 1.  False-positive radioiodine uptake in a functional ovarian cyst in a patient treated with total thyroidectomy for papillary cancer.

Authors:  Hye Yoon Jang; Bo Hyun Kim; Won Jin Kim; Yun Kyung Jeon; Sang Soo Kim; Yong Ki Kim; In Ju Kim
Journal:  Intern Med       Date:  2013       Impact factor: 1.271

2.  Hypothyroidism as a late sequela in patient with Graves' disease treated with antithyroid agents.

Authors:  L C Wood; S H Ingbar
Journal:  J Clin Invest       Date:  1979-11       Impact factor: 14.808

3.  Low serum thyroglobulin as a clue to the diagnosis of thyrotoxicosis factitia.

Authors:  S Mariotti; E Martino; C Cupini; R Lari; C Giani; L Baschieri; A Pinchera
Journal:  N Engl J Med       Date:  1982-08-12       Impact factor: 91.245

4.  The age of patients with thyrotoxicosis factitia in Italy from 1973 to 1996.

Authors:  F Bogazzi; L Bartalena; G Scarcello; A Campomori; G Rossi; E Martino
Journal:  J Endocrinol Invest       Date:  1999-02       Impact factor: 4.256

5.  The measurement of fecal thyroxine in the diagnosis of thyrotoxicosis factitia.

Authors:  R Bouillon; L Verresen; F Staels; M Bex; P De Vos; M De Roo
Journal:  Thyroid       Date:  1993       Impact factor: 6.568

6.  Thyroglobulin autoantibody levels below the cut-off for positivity can interfere with thyroglobulin measurement.

Authors:  J M Cubero; J Rodríguez-Espinosa; C Gelpi; M Estorch; R Corcoy
Journal:  Thyroid       Date:  2003-07       Impact factor: 6.568

7.  Thyrotoxicosis factitia masquerading as recurrent Graves' disease: endogenous antibody immunoassay interference, a pitfall for the unwary.

Authors:  V R Jahagirdar; P Strouhal; G Holder; R Gama; B M Singh
Journal:  Ann Clin Biochem       Date:  2008-05       Impact factor: 2.057

Review 8.  Can we interpret serum thyroglobulin results?

Authors:  Penny Clark; Jayne Franklyn
Journal:  Ann Clin Biochem       Date:  2012-05-15       Impact factor: 2.057

9.  A thyrotoxicosis outbreak due to dietary pills in Paris.

Authors:  Vincent Ioos; Vincent Das; Eric Maury; Jean-Luc Baudel; Jérôme Guéchot; Bertrand Guidet; Georges Offenstadt
Journal:  Ther Clin Risk Manag       Date:  2008-12       Impact factor: 2.423

  9 in total

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