Valérie Siroux1, Emmanuelle Bouzigon2. 1. Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, INSERM U1209, CNRS, University Grenoble Alpes, Institute for Advanced Biosciences, Grenoble, France. Electronic address: valerie.siroux@univ-grenoble-alpes.fr. 2. INSERM UMRS 1124, Team of Genetic Epidemiology and Functional Genomics of Multifactorial Diseases, University Paris Descartes, Paris, France.