Literature DB >> 3103550

Prostaglandin metabolism in umbilical vessels of smoking and non-smoking mothers.

C Dadak, J Deutinger, A Reinthaller, J Neumark, C Hoche.   

Abstract

Arachidonic acid (AA) and its metabolites are responsible for the regulation of the umbilical blood flow. We investigated the prostaglandin (PG) synthesis in umbilical arteries and veins of 16 smoking and 17 non-smoking mothers. AA and PGs were analyzed after extraction of samples by means of thin layer chromatography (TLC). Of all the AA metabolites in umbilical arteries and veins, prostacyclin reached the highest concentration. In non-smoking mothers the conversion rate of AA in arteries and veins was similar. The only exception was PGE2 which showed a significantly lower concentration in umbilical veins of smoking mothers. However, the influence of PGE2 on the blood flow of umbilical arteries and veins seems to be of minor importance compared to other vessels.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3103550     DOI： 10.1007/bf02134058

Source DB:  PubMed          Journal:  Arch Gynecol        ISSN： 0170-9925


  10 in total

1.  Prostacyclin and human foetal circulation.

Authors:  G Remuzzi; R Misiani; D Muratore; D Marchesi; M Livio; A Schieppati; G Mecca; G de Gaetano; M B Donati
Journal:  Prostaglandins       Date:  1979-09

2.  [Results of placental circulation measurements in hazard pregnancies].

Authors:  H Janisch; S Leodolter
Journal:  Z Geburtshilfe Perinatol       Date:  1973-04

3.  Diminished prostacyclin formation in umbilical arteries of babies born to women who smoke.

Authors:  C Dadak; C Leithner; H Sinzinger; K Silberbauer
Journal:  Lancet       Date:  1981-01-10       Impact factor: 79.321

4.  [Ultrastructure findings in umbilical cord arteries in EPH gestosis, juvenile diabetes mellitus and mothers who smoke].

Authors:  W Ulrich; C Dadak; H Sinzinger
Journal:  Vasa       Date:  1984       Impact factor: 1.961

5.  Fetal umbilical artery flow velocity waveforms and placental resistance: clinical significance.

Authors:  B J Trudinger; W B Giles; C M Cook; J Bombardieri; L Collins
Journal:  Br J Obstet Gynaecol       Date:  1985-01

6.  Intimal ultrastructure of human umbilical arteries. Observations on arteries from newborn children of smoking and nonsmoking mothers.

Authors:  I Asmussen; K Kjeldsen
Journal:  Circ Res       Date:  1975-05       Impact factor: 17.367

7.  An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation.

Authors:  S Moncada; R Gryglewski; S Bunting; J R Vane
Journal:  Nature       Date:  1976-10-21       Impact factor: 49.962

8.  Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation.

Authors:  S Moncada; E A Higgs; J R Vane
Journal:  Lancet       Date:  1977-01-01       Impact factor: 79.321

9.  Reduced umbilical artery prostacyclin formation in complicated pregnancies.

Authors:  C Dadak; A Kefalides; H Sinzinger; G Weber
Journal:  Am J Obstet Gynecol       Date:  1982-12-01       Impact factor: 8.661

10.  Uteroplacental blood flow velocity-time waveforms in normal and complicated pregnancy.

Authors:  B J Trudinger; W B Giles; C M Cook
Journal:  Br J Obstet Gynaecol       Date:  1985-01
  10 in total
  1 in total

Review 1.  Risks and benefits of nicotine to aid smoking cessation in pregnancy.

Authors:  D A Dempsey; N L Benowitz
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.