Objectives: To evaluate the frequency of post-concussion symptoms and prevalence and risk factors of post-concussion syndrome (PCS) in the general population, investigate the association between the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and self-perceived health, and evaluate differences between three European countries. Methods: A web-based survey including the RPQ and EQ-5D was conducted among representative samples in three European countries. Results: A total of 11,759 respondents completed the questionnaire. The most frequently reported symptom was fatigue (49.9%). Almost half (45.1%) of the respondents were classified as having PCS considering rating score 2 (three RPQ items with score ≥ 2) as a cut-off. Chronic health complaints were found as a significant risk factor for PCS. All items of the RPQ were positively correlated with the EQ-5D and the strongest positive correlation (0.633, p<0.001) was between RPQ item 'feeling depressed or tearful' and EQ-5D domain 'anxiety/depression'. Conclusions: We found a high frequency of post-concussion-like symptoms and PCS in the general population, indicating that these symptoms are not specific for patients with traumatic brain injury (TBI), and PCS is not a unique syndrome after TBI. Therefore, the use of post-concussion symptoms and PCS as outcome following mild TBI should be interpreted with caution.
Objectives: To evaluate the frequency of post-concussion symptoms and prevalence and risk factors of post-concussion syndrome (PCS) in the general population, investigate the association between the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) and self-perceived health, and evaluate differences between three European countries. Methods: A web-based survey including the RPQ and EQ-5D was conducted among representative samples in three European countries. Results: A total of 11,759 respondents completed the questionnaire. The most frequently reported symptom was fatigue (49.9%). Almost half (45.1%) of the respondents were classified as having PCS considering rating score 2 (three RPQ items with score ≥ 2) as a cut-off. Chronic health complaints were found as a significant risk factor for PCS. All items of the RPQ were positively correlated with the EQ-5D and the strongest positive correlation (0.633, p<0.001) was between RPQ item 'feeling depressed or tearful' and EQ-5D domain 'anxiety/depression'. Conclusions: We found a high frequency of post-concussion-like symptoms and PCS in the general population, indicating that these symptoms are not specific for patients with traumatic brain injury (TBI), and PCS is not a unique syndrome after TBI. Therefore, the use of post-concussion symptoms and PCS as outcome following mild TBI should be interpreted with caution.
Authors: Joan Machamer; Nancy Temkin; Sureyya Dikmen; Lindsay D Nelson; Jason Barber; Phillip Hwang; Kim Boase; Murray B Stein; Xiaoying Sun; Joseph Giacino; Michael A McCrea; Sabrina R Taylor; Sonia Jain; Geoff Manley Journal: J Neurotrauma Date: 2022-02-09 Impact factor: 5.269
Authors: Aliyah Snyder; Christopher Sheridan; Alexandra Tanner; Kevin Bickart; Molly Sullan; Michelle Craske; Meeryo Choe; Talin Babikian; Christopher Giza; Robert Asarnow Journal: J Clin Med Date: 2021-02-03 Impact factor: 4.241
Authors: Daphne C Voormolen; Juanita A Haagsma; Suzanne Polinder; Andrew I R Maas; Ewout W Steyerberg; Petar Vuleković; Charlie A Sewalt; Benjamin Y Gravesteijn; Amra Covic; Nada Andelic; Anne Marie Plass; Nicole von Steinbuechel Journal: J Clin Med Date: 2019-11-08 Impact factor: 4.241