Literature DB >> 31032628

Epidemiological profile of individuals diagnosed with HIV: results from the preliminary phase of case-based surveillance in Kenya.

Richelle Harklerode1, Wanjiru Waruiru2, Felix Humwa2, Anthony Waruru3, Timothy Kellogg1, Lilly Muthoni4, James Macharia2, Emily Zielinski-Gutierrez3.   

Abstract

Understanding the characteristics of individuals who are newly diagnosed with HIV is critical to controlling the HIV epidemic. Characterizing this population can improve strategies to identify undiagnosed positives and assist in targeting the provision of HIV services to improve health outcomes. We describe the characteristics of newly diagnosed HIV cases in western Kenya from 124 health facilities. The study cohort cases were matched to prevent duplication and patients newly diagnosed between January and June 2015 were identified and descriptive analysis performed. Among 8664 newly identified HIV cases, during the pilot timeframe, 3.1% (n=265) had retested for HIV after initial diagnosis. Linkage to care was recorded for approximately half (45.3%, n = 3930) and 28.0% (n = 2425) had a CD4 count available during the pilot timeframe. The median baseline CD4 count was 332 cells/mL (IQR: 156-544). Among the newly diagnosed age 15 years or older with a CD4 test, 53.0% (n = 1216) were diagnosed late, including 32.9% (n = 755) who had advanced HIV at diagnosis. Factors associated with late diagnosis included being male and in an age group older than 34 years. In western Kenya, continued efforts are needed in the area of testing to enhance early HIV diagnosis and epidemic control.

Entities:  

Keywords:  HIV; HIV diagnosis; HIV surveillance; descriptive epidemiology

Year:  2019        PMID: 31032628      PMCID: PMC6815685          DOI: 10.1080/09540121.2019.1612021

Source DB:  PubMed          Journal:  AIDS Care        ISSN: 0954-0121


  21 in total

1.  Association of initial CD4 cell count and viral load with response to highly active antiretroviral therapy.

Authors:  R E Chaisson; J C Keruly; R D Moore
Journal:  JAMA       Date:  2000-12-27       Impact factor: 56.272

2.  The undiagnosed HIV epidemic in France and its implications for HIV screening strategies.

Authors:  Virginie Supervie; Jacques D A Ndawinz; Sara Lodi; Dominique Costagliola
Journal:  AIDS       Date:  2014-07-31       Impact factor: 4.177

3.  Factors Associated with Late Engagement to HIV Care in Western Kenya: A Cross-Sectional Study.

Authors:  Charles Meja Kwobah; Paula Braitstein; Julius K Koech; Gilbert Simiyu; Ann W Mwangi; Kara Wools-Kaloustian; Abraham M Siika
Journal:  J Int Assoc Provid AIDS Care       Date:  2015-01-14

4.  Characteristics of HIV infected patients cared for at "academic model for the prevention and treatment of HIV/AIDS" clinics in western Kenya.

Authors:  L O Diero; D Shaffer; S Kimaiyo; A M Siika; J K Rotich; F E Smith; J J Mamlin; R M Einterz; A C Justice; E J Carter; W M Tierney
Journal:  East Afr Med J       Date:  2006-08

5.  HIV testing experiences and their implications for patient engagement with HIV care and treatment on the eve of 'test and treat': findings from a multicountry qualitative study.

Authors:  Alison Wringe; Mosa Moshabela; Constance Nyamukapa; Dominic Bukenya; Ken Ondenge; William Ddaaki; Joyce Wamoyi; Janet Seeley; Kathryn Church; Basia Zaba; Victoria Hosegood; Oliver Bonnington; Morten Skovdal; Jenny Renju
Journal:  Sex Transm Infect       Date:  2017-07       Impact factor: 3.519

6.  Late presenters in the era of highly active antiretroviral therapy: uptake of and responses to antiretroviral therapy.

Authors:  Caroline A Sabin; Colette J Smith; Helen Gumley; Gabrielle Murphy; Fiona C Lampe; Andrew N Phillips; Beth Prinz; Mike Youle; Margaret A Johnson
Journal:  AIDS       Date:  2004-11-05       Impact factor: 4.177

7.  Admission characteristics, diagnoses and outcomes of HIV-infected patients registered in an ambulatory HIV-care programme in western Kenya.

Authors:  A M Siika; P O Ayuo; Mwangi J E Sidle; K Wools-Kaloustian; S N Kimaiyo; W M Tierney
Journal:  East Afr Med J       Date:  2008-11

Review 8.  HIV testing and care in Burkina Faso, Kenya, Malawi and Uganda: ethics on the ground.

Authors:  Carla Makhlouf Obermeyer; Sarah Bott; Ron Bayer; Alice Desclaux; Rachel Baggaley
Journal:  BMC Int Health Hum Rights       Date:  2013-01-23

9.  Risk factors and outcomes for late presentation for HIV-positive persons in Europe: results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE).

Authors:  Amanda Mocroft; Jens D Lundgren; Miriam Lewis Sabin; Antonella d'Arminio Monforte; Norbert Brockmeyer; Jordi Casabona; Antonella Castagna; Dominique Costagliola; Francois Dabis; Stéphane De Wit; Gerd Fätkenheuer; Hansjakob Furrer; Anne M Johnson; Marios K Lazanas; Catherine Leport; Santiago Moreno; Niels Obel; Frank A Post; Joanne Reekie; Peter Reiss; Caroline Sabin; Adriane Skaletz-Rorowski; Ignacio Suarez-Lozano; Carlo Torti; Josiane Warszawski; Robert Zangerle; Céline Fabre-Colin; Jesper Kjaer; Genevieve Chene; Jesper Grarup; Ole Kirk
Journal:  PLoS Med       Date:  2013-09-03       Impact factor: 11.069

10.  The status of HIV testing and counseling in Kenya: results from a nationally representative population-based survey.

Authors:  Anne Ng'ang'a; Wanjiru Waruiru; Carol Ngare; Victor Ssempijja; Thomas Gachuki; Inviolata Njoroge; Patricia Oluoch; Davies O Kimanga; William K Maina; Rex Mpazanje; Andrea A Kim
Journal:  J Acquir Immune Defic Syndr       Date:  2014-05-01       Impact factor: 3.731

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