BACKGROUND: To evaluate the prevalence of Klippel-Feil syndrome (KFS) in pediatric patients obtaining cervical CT imaging in the emergency room (ER). METHODS: We evaluated CT scans of the cervical spine of pediatric patients treated in the ER of a Level I Trauma Center from January 2013 to December 2015. Along with analysis of the CT scans for KFS, the following demographics were collected: age, sex, race and ethnicity. Mechanism of injury was also established for all patients. If KFS was present, it was classified using Samartzis classification as type I (single level fusion), type II (multiple, noncontiguous fused segments) or type III (multiple, contiguous fused segments). RESULTS: Of the 848 cervical CTs taken for pediatric ER patients during the study period, 831 were included. Of these patients, 10 had KFS, a prevalence of 1.2%. According to Samartzis classification, 9 were type I and 1 type III. The average age of patients with KFS was 16.02 years (10-18 years), with 8 males (80%) and 2 females (20%). Three had congenital fusions at vertebral levels C2-C3, two at C3-C4, three at C5-C6, one at C6-C7, and one with multiple levels of cervical fusion. CONCLUSIONS: The prevalence of KFS amongst 831 pediatric patients, who underwent cervical CT imaging over a 3-year period, was 1.2% (approximately 1 in 83). The most commonly fused spinal levels were C2-C3 and C5-C6. The prevalence of KFS in our study was higher than previously described, and thus warrants monitoring.
BACKGROUND: To evaluate the prevalence of Klippel-Feil syndrome (KFS) in pediatric patients obtaining cervical CT imaging in the emergency room (ER). METHODS: We evaluated CT scans of the cervical spine of pediatric patients treated in the ER of a Level I Trauma Center from January 2013 to December 2015. Along with analysis of the CT scans for KFS, the following demographics were collected: age, sex, race and ethnicity. Mechanism of injury was also established for all patients. If KFS was present, it was classified using Samartzis classification as type I (single level fusion), type II (multiple, noncontiguous fused segments) or type III (multiple, contiguous fused segments). RESULTS: Of the 848 cervical CTs taken for pediatric ER patients during the study period, 831 were included. Of these patients, 10 had KFS, a prevalence of 1.2%. According to Samartzis classification, 9 were type I and 1 type III. The average age of patients with KFS was 16.02 years (10-18 years), with 8 males (80%) and 2 females (20%). Three had congenital fusions at vertebral levels C2-C3, two at C3-C4, three at C5-C6, one at C6-C7, and one with multiple levels of cervical fusion. CONCLUSIONS: The prevalence of KFS amongst 831 pediatric patients, who underwent cervical CT imaging over a 3-year period, was 1.2% (approximately 1 in 83). The most commonly fused spinal levels were C2-C3 and C5-C6. The prevalence of KFS in our study was higher than previously described, and thus warrants monitoring.
Authors: E González-Reimers; A Mas-Pascual; M Arnay-De-La-Rosa; J Velasco-Vásquez; M C Jiménez-Gómez Journal: Ann Rheum Dis Date: 2001-02 Impact factor: 19.103
Authors: May Tassabehji; Zhi Ming Fang; Emma N Hilton; Julie McGaughran; Zhongming Zhao; Charles E de Bock; Emma Howard; Michael Malass; Dian Donnai; Ashish Diwan; Forbes D C Manson; Dédée Murrell; Raymond A Clarke Journal: Hum Mutat Date: 2008-08 Impact factor: 4.878
Authors: Dino Samartzis; John P Lubicky; Jean Herman; Prakasam Kalluri; Francis H Shen Journal: Spine (Phila Pa 1976) Date: 2006-05-15 Impact factor: 3.468
Authors: Dino Samartzis; Prakasam Kalluri; Jean Herman; John P Lubicky; Francis H Shen Journal: Spine (Phila Pa 1976) Date: 2008-06-01 Impact factor: 3.468