Literature DB >> 31028208

Perioperative Management in Patients With Undergoing Direct Oral Anticoagulant Therapy in Oral Surgery - A Multicentric Questionnaire Survey.

Clarissa Precht1, Yeliz Demirel1, Reinhard E Friedrich2, Johannes Wikner1, Alexandre T Assaf1, Hans O Pinnschmidt3, Christian Knipfer1, Henning Hanken1.   

Abstract

AIM: The purpose of this study was to survey the current opinions of hospitals and medical practices concerning the perioperative management of patients undergoing direct oral anticoagulant therapy (DOAC) and discuss recommendations for the clinical practice.
MATERIALS AND METHODS: A questionnaire with 13 topics and multiple ordinal-polytomous subitems was designed and sent to 120 Departments of Oral and Maxillofacial Surgery in Austria, Switzerland and Germany, as well as to 85 oral and maxillofacial/oral surgeons in medical offices in Hamburg, Germany. The data were statistically evaluated by Chi-square, Fisher's exact and Jonckheere-Terpstra tests.
RESULTS: The rate of response was 42%. Thirty-seven percent of respondents reported treating over 50 patients per year with undergoing DOAC therapy and only 18% assess a high bleeding risk [33% for vitamin K antagonists (VKA)]. In contrast to that, 62% of respondents would interrupt the DOAC therapy for extraction of one tooth, while 94% would continue VKA therapy. Significantly more clinicians apply suture than those in a medical office. The use of additional hemostatic measures varied between clinic and medical practice. There was a clear request for more detailed guidelines.
CONCLUSION: The study shows the current opinion for perioperative management of patients undergoing DOAC therapy. Multi-centric studies under controlled conditions are needed for a safer treatment of anticoagulated patients as therapy strategies differ greatly between institutions and therefore a complication analysis is hardly possible. Copyright
© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Postoperative bleeding; dental surgery; direct oral anticoagulant therapy; vitamin K antagonist

Mesh:

Substances:

Year:  2019        PMID: 31028208      PMCID: PMC6559883          DOI: 10.21873/invivo.11550

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.155


  2 in total

1.  Risk factors for bleeding after dental extractions in patients receiving antithrombotic drugs - A case control study.

Authors:  Jinxia Huang; Jie Liu; Haitao Shi; Jun Wu; Jiyuan Liu; Jian Pan
Journal:  J Dent Sci       Date:  2021-10-20       Impact factor: 3.719

2.  Bleeding Complications in Anticoagulated and/or Antiplatelet-Treated Patients at the Dental Office: A Retrospective Study.

Authors:  Esther Martínez-Moreno; Federico Martínez-López; Francisco Javier Rodríguez-Lozano; Ricardo Elías Oñate-Sánchez
Journal:  Int J Environ Res Public Health       Date:  2021-02-08       Impact factor: 3.390

  2 in total

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