Literature DB >> 31028182

The Role of ARID1A in Endometrial Cancer and the Molecular Pathways Associated With Pathogenesis and Cancer Progression.

Chrisavgi Toumpeki1, Anastasios Liberis2, Ioannis Tsirkas1, Theodora Tsirka3, Sofia Kalagasidou4, Lola Inagamova1, Xanthoula Anthoulaki1, Georgios Tsatsaris1, Emmanuel N Kontomanolis5.   

Abstract

AT-rich interaction domain 1A gene (ARID1A) encodes for a subunit of the switch/sucrose non-fermentable (SWI/SNF) complex, a chromatin remodeling complex, and it has been implicated in the pathogenesis of various cancer types. In this review, we discuss how ARID1A is linked to endometrial cancer and what molecular pathways are affected by mutation or inhibition of ARID1A. We also discuss the potential use of ARID1A not only as a prognostic biomarker, but also as a target for therapeutic interventions. Copyright
© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  ARID1A; endometrial cancer; molecular pathways; review

Mesh：

Substances：

Year:  2019        PMID： 31028182      PMCID： PMC6559907          DOI： 10.21873/invivo.11524

Source DB:  PubMed          Journal:  In Vivo        ISSN： 0258-851X            Impact factor:   2.155


  11 in total

Review 1.  High-intermediate risk endometrial cancer: moving toward a molecularly based risk assessment profile.

Authors:  Tavonna D Kako; Maahum Z Kamal; Jhalak Dholakia; Carly B Scalise; Rebecca C Arend
Journal:  Int J Clin Oncol       Date:  2022-01-17       Impact factor: 3.402

2.  Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency, CD8+ TIL infiltration, and provides no independent prognostic value in endometriosis-associated ovarian carcinomas.

Authors:  Karolin Heinze; Tayyebeh M Nazeran; Sandra Lee; Pauline Krämer; Evan S Cairns; Derek S Chiu; Samuel Cy Leung; Eun Young Kang; Nicola S Meagher; Catherine J Kennedy; Jessica Boros; Friedrich Kommoss; Hans-Walter Vollert; Florian Heitz; Andreas du Bois; Philipp Harter; Marcel Grube; Bernhard Kraemer; Annette Staebler; Felix Kf Kommoss; Sabine Heublein; Hans-Peter Sinn; Naveena Singh; Angela Laslavic; Esther Elishaev; Alex Olawaiye; Kirsten Moysich; Francesmary Modugno; Raghwa Sharma; Alison H Brand; Paul R Harnett; Anna DeFazio; Renée T Fortner; Jan Lubinski; Marcin Lener; Aleksandra Tołoczko-Grabarek; Cezary Cybulski; Helena Gronwald; Jacek Gronwald; Penny Coulson; Mona A El-Bahrawy; Michael E Jones; Minouk J Schoemaker; Anthony J Swerdlow; Kylie L Gorringe; Ian Campbell; Linda Cook; Simon A Gayther; Michael E Carney; Yurii B Shvetsov; Brenda Y Hernandez; Lynne R Wilkens; Marc T Goodman; Constantina Mateoiu; Anna Linder; Karin Sundfeldt; Linda E Kelemen; Aleksandra Gentry-Maharaj; Martin Widschwendter; Usha Menon; Kelly L Bolton; Jennifer Alsop; Mitul Shah; Mercedes Jimenez-Linan; Paul Dp Pharoah; James D Brenton; Kara L Cushing-Haugen; Holly R Harris; Jennifer A Doherty; Blake Gilks; Prafull Ghatage; David G Huntsman; Gregg S Nelson; Anna V Tinker; Cheng-Han Lee; Ellen L Goode; Brad H Nelson; Susan J Ramus; Stefan Kommoss; Aline Talhouk; Martin Köbel; Michael S Anglesio
Journal:  J Pathol       Date:  2022-02-07       Impact factor: 9.883

Review 3.  The Role of CTNNB1 in Endometrial Cancer.

Authors:  Živa Ledinek; Monika Sobočan; Jure Knez
Journal:  Dis Markers       Date:  2022-04-28       Impact factor: 3.464

Review 4.  Development of New Cancer Treatment by Identifying and Focusing the Genetic Mutations or Altered Expression in Gynecologic Cancers.

Authors:  Yun-Hsin Tang; Chiao-Yun Lin; Chyong-Huey Lai
Journal:  Genes (Basel)       Date:  2021-10-09       Impact factor: 4.096

5.  Prognosis Stratification Tools in Early-Stage Endometrial Cancer: Could We Improve Their Accuracy?

Authors:  Jorge Luis Ramon-Patino; Ignacio Ruz-Caracuel; Victoria Heredia-Soto; Luis Eduardo Garcia de la Calle; Bulat Zagidullin; Yinyin Wang; Alberto Berjon; Alvaro Lopez-Janeiro; Maria Miguel; Javier Escudero; Alejandro Gallego; Beatriz Castelo; Laura Yebenes; Alicia Hernandez; Jaime Feliu; Alberto Pelaez-García; Jing Tang; David Hardisson; Marta Mendiola; Andres Redondo
Journal:  Cancers (Basel)       Date:  2022-02-12       Impact factor: 6.639

Review 6.  Roles of ARID1A variations in colorectal cancer: a collaborative review.

Authors:  Shankun Zhao; Weizhou Wu; Zufu Jiang; Fuqin Tang; Lingzhi Ding; Weifang Xu; Libin Ruan
Journal:  Mol Med       Date:  2022-04-14       Impact factor: 6.354

7.  Endometrial cancer prognosis in women with endometriosis and adenomyosis: A retrospective nationwide cohort study of 40 840 women.

Authors:  Marjolein Hermens; Anne M van Altena; Maaike van der Aa; Johan Bulten; Huib A A M van Vliet; Albert G Siebers; Ruud L M Bekkers
Journal:  Int J Cancer       Date:  2021-12-27       Impact factor: 7.316

Review 8.  A Review of the Clinical Characteristics and Novel Molecular Subtypes of Endometrioid Ovarian Cancer.

Authors:  Shuangfeng Chen; Yuebo Li; Lili Qian; Sisi Deng; Luwen Liu; Weihua Xiao; Ying Zhou
Journal:  Front Oncol       Date:  2021-06-03       Impact factor: 6.244

Review 9.  Actionable Potentials of Less Frequently Mutated Genes in Colorectal Cancer and Their Roles in Precision Medicine.

Authors:  Ryia Illani Mohd Yunos; Nurul Syakima Ab Mutalib; Francis Yew Fu Tieng; Nadiah Abu; Rahman Jamal
Journal:  Biomolecules       Date:  2020-03-20

10.  ARID1A knockdown enhances carcinogenesis features and aggressiveness of Caco-2 colon cancer cells: An in vitro cellular mechanism study.

Authors:  Paleerath Peerapen; Kanyarat Sueksakit; Wanida Boonmark; Sunisa Yoodee; Visith Thongboonkerd
Journal:  J Cancer       Date:  2022-01-01       Impact factor: 4.207
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