Literature DB >> 3102562

Light chains and the kidney.

J R Bradley, S Thiru, D B Evans.   

Abstract

Five cases of renal impairment caused by the deposition of light chains in the kidney in association with various immunoproliferative disorders are reported. Light microscopy, immunohistochemistry, and electron microscopy were undertaken and different clinical courses were studied, resulting in variable influences of treatment. Light chain deposition is an important cause of renal impairment and requires special histological techniques for its recognition.

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Year:  1987        PMID： 3102562      PMCID： PMC1140828          DOI： 10.1136/jcp.40.1.53

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  8 in total

1.  Acute renal failure in multiple myeloma.

Authors:  R A Defronzo; R L Humphrey; J R Wright; C R Cooke
Journal:  Medicine (Baltimore)       Date:  1975-05       Impact factor: 1.889

2.  Fibrillar assemblage of variable segments of immunoglobulin light chains: an electron microscopic study.

Authors:  T Shirahama; M D Benson; A S Cohen; A Tanaka
Journal:  J Immunol       Date:  1973-01       Impact factor: 5.422

3.  The formation of amyloid-like fibrils in vitro from Bence Jones Proteins of the VlambdaI subclass.

Authors:  R P Linke; F W Tischendorf; D Zucker-Franklin; E C Franklin
Journal:  J Immunol       Date:  1973-07       Impact factor: 5.422

4.  Renal granular monoclonal light chain deposits: morphological aspects in 11 cases.

Authors:  L H Noel; D Droz; D Ganeval; J P Grunfeld
Journal:  Clin Nephrol       Date:  1984-05       Impact factor: 0.975

5.  The importance of urinary immunoglobulin light chain isoelectric point (pI) in nephrotoxicity in multiple myeloma.

Authors:  R A Coward; I W Delamore; N P Mallick; E L Robinson
Journal:  Clin Sci (Lond)       Date:  1984-02       Impact factor: 6.124

6.  The renal handling of low molecular weight proteins. II. Disorders of serum protein catabolism in patients with tubular proteinuria, the nephrotic syndrome, or uremia.

Authors:  T A Waldmann; W Strober; R P Mogielnicki
Journal:  J Clin Invest       Date:  1972-08       Impact factor: 14.808

7.  Light chain nephropathy.

Authors:  R R Tubbs; G N Gephardt; J T McMahon; P M Hall; R Valenzuela; D G Vidt
Journal:  Am J Med       Date:  1981-08       Impact factor: 4.965

8.  Synthesis of abnormal immunoglobulins in lymphoplasmacytic disorders with visceral light chain deposition.

Authors:  J L Preud'homme; L Morel-Maroger; J C Brouet; M Cerf; F Mignon; P Guglielmi; M Seligmann
Journal:  Am J Med       Date:  1980-11       Impact factor: 4.965
  8 in total
  1 in total

1.  Light chain deposition disease neuropathy resembling amyloid neuropathy in a multiple myeloma patient.

Authors:  M P Grassi; F Clerici; C Perin; M Borella; A Gendarini; A Quattrini; R Nemni; A Mangoni
Journal:  Ital J Neurol Sci       Date:  1998-08
  1 in total

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