| Literature DB >> 31025392 |
Hyungjong Park1,2, Jayoung Kim1, Jimin Ha1, In Gun Hwang1, Tae-Jin Song3, Joonsang Yoo2, Seong Hwan Ahn4, Kyoungsub Kim1, Byung Moon Kim5, Dong Joon Kim5, Young Dae Kim1, Hyo Suk Nam1, Il Kwon1, Hyun-Jung Choi6, Sung-Il Sohn2, Hye Sun Lee7, Ji Hoe Heo1.
Abstract
The histological features of thrombus in stroke patients with cancer are not well known. Using immunohistochemical staining of thrombi retrieved during mechanical thrombectomy in stroke patients, thrombus compositions were compared between 16 patients with active cancer, 16 patients with inactive cancer, and 16 patients without any history of cancer. The active cancer group showed higher platelet and lower erythrocyte fractions than the inactive cancer or the control group. Four patients with vegetation showed very high platelet and low erythrocyte fractions. Patients with cryptogenic etiology in the active cancer group showed a similar pattern to those with vegetation. These findings may aid the determination of treatment strategies in cancer-associated stroke. ANN NEUROL 2019.Entities:
Year: 2019 PMID： 31025392 DOI： 10.1002/ana.25495
Source DB: PubMed Journal: Ann Neurol ISSN： 0364-5134 Impact factor: 10.422