Omar Helal1, Gerd Göstemeyer1, Joachim Krois1, Karim Fawzy El Sayed2,3, Christian Graetz2, Falk Schwendicke1. 1. Department of Operative and Preventive Dentistry, Charité University of Berlin, Berlin, Germany. 2. Clinic of Conservative Dentistry and Periodontology, University of Kiel, Kiel, Germany. 3. Oral Medicine and Periodontology Department, Faculty of Oral and Dental Medicine, Cairo, Egypt.
Abstract
AIM: A range of predictors for tooth loss in periodontitis patients have been reported. We performed a systematic review and meta-analysis to assess the consistency and magnitude of any association between a total of 12 predictors and tooth loss. MATERIALS AND METHODS: Medline/Embase/Central were searched for longitudinal studies investigating the association between predictors and tooth loss in periodontitis patients. Random-effects meta-analysis was performed, and study quality assessed. RESULTS: Twenty studies (15,422 patients, mean follow-up: 12 years) were included. The mean annual tooth loss/patient was 0.12 (min./max: 0.01/0.36). Older patients (n = 8 studies; OR: 1.05, 95% CI: 1.03-1.08/year), non-compliant ones (n = 11; 1.51, 1.06-2.16), diabetics (n = 7; 1.80, 1.26-2.57), those with IL-1-polymorphism (n = 3; 1.80; 1.29-2.52) and smokers (n = 15; 1.98, 1.58-2.48) had a significantly higher risk of tooth loss. Teeth with bone loss (n = 3; 1.04, 1.03-1.05/%), high probing pocket depth (n = 6; 3.19, 1.70-5.98), mobility (n = 4; 3.71, 1.65-8.38) and molars (n = 4; 4.22, 2.12-8.39), especially with furcation involvement (n = 5; 2.68, 1.75-4.08) also showed higher risks. Gender (n = 16; 0.95, 0.86-1.05) and endodontic affection (n = 3; 3.62, 0.99-13.2) were not significantly associated with tooth loss. CONCLUSIONS: Older, non-compliant, smoking or diabetic patients, and teeth with bone loss, high probing pocket depth, mobility, or molars, especially with furcation involvement showed higher risks of tooth loss.
AIM: A range of predictors for tooth loss in periodontitispatients have been reported. We performed a systematic review and meta-analysis to assess the consistency and magnitude of any association between a total of 12 predictors and tooth loss. MATERIALS AND METHODS: Medline/Embase/Central were searched for longitudinal studies investigating the association between predictors and tooth loss in periodontitispatients. Random-effects meta-analysis was performed, and study quality assessed. RESULTS: Twenty studies (15,422 patients, mean follow-up: 12 years) were included. The mean annual tooth loss/patient was 0.12 (min./max: 0.01/0.36). Older patients (n = 8 studies; OR: 1.05, 95% CI: 1.03-1.08/year), non-compliant ones (n = 11; 1.51, 1.06-2.16), diabetics (n = 7; 1.80, 1.26-2.57), those with IL-1-polymorphism (n = 3; 1.80; 1.29-2.52) and smokers (n = 15; 1.98, 1.58-2.48) had a significantly higher risk of tooth loss. Teeth with bone loss (n = 3; 1.04, 1.03-1.05/%), high probing pocket depth (n = 6; 3.19, 1.70-5.98), mobility (n = 4; 3.71, 1.65-8.38) and molars (n = 4; 4.22, 2.12-8.39), especially with furcation involvement (n = 5; 2.68, 1.75-4.08) also showed higher risks. Gender (n = 16; 0.95, 0.86-1.05) and endodontic affection (n = 3; 3.62, 0.99-13.2) were not significantly associated with tooth loss. CONCLUSIONS: Older, non-compliant, smoking or diabeticpatients, and teeth with bone loss, high probing pocket depth, mobility, or molars, especially with furcation involvement showed higher risks of tooth loss.
Authors: Anne Thea Tveit Sødal; Lene Hystad Hove; My Tien Diep; Rasa Skudutyte-Rysstad; Odd Carsten Koldsland Journal: BMC Oral Health Date: 2022-06-21 Impact factor: 3.747
Authors: Roko Duplancic; Marija Roguljic; Ivan Puhar; Nika Vecek; Ruzica Dragun; Katarina Vukojevic; Mirna Saraga-Babic; Darko Kero Journal: Front Physiol Date: 2019-09-25 Impact factor: 4.566
Authors: Sanjay Jyothish; Athanasios E Athanasiou; Miltiadis A Makrygiannakis; Eleftherios G Kaklamanos Journal: PLoS One Date: 2021-02-17 Impact factor: 3.240