Literature DB >> 3102251

Expression of Pgp-1 (or Ly24) by subpopulations of mouse thymocytes and activated peripheral T lymphocytes.

F Lynch, G Chaudhri, J E Allan, P C Doherty, R Ceredig.   

Abstract

The expression of Pgp-1 (Ly24) by subpopulations of thymocytes was investigated and a subpopulation of Lyt-2-/L3T4-/J11d- thymocytes was identified which contained significant numbers (80%) of Pgp-1+ cells. Among freshly isolated lymph node T cells but not cortisone-resistant thymocytes, Pgp-1 expression was heterogeneous. Stimulation of T lymphocytes with either concanavalin A or the combination of phorbol myristate acetate plus calcium ionophore resulted in increased Pgp-1 expression which was found to be regulated independently of DNA synthesis and interleukin 2 receptor expression. T cells in the cerebrospinal fluid exudate of mice infected with lymphocytic choriomeningitis virus were also found to be Pgp-1+.

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Year:  1987        PMID： 3102251     DOI： 10.1002/eji.1830170123

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  7 in total

1.  Evolution of CD4 T-cell subsets following infection of naive and memory immune mice with Mycobacterium tuberculosis.

Authors:  J P Griffin; I M Orme
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

Review 2.  Molecular biological definition of the prothymocyte: problems of commitment and lineage promiscuity.

Authors:  A E Silverstone; M A Yuille
Journal:  Immunol Res       Date:  1987       Impact factor: 2.829

Review 3.  Phenotypic analysis of mouse thymus development.

Authors:  R Ceredig; F Lynch; J Medveczky
Journal:  Immunol Res       Date:  1988       Impact factor: 2.829

4.  Characterization of a 95,000 molecule on sheep leucocytes homologous to murine Pgp-1 and human CD44.

Authors:  C R Mackay; J F Maddox; G L Wijffels; I R Mackay; I D Walker
Journal:  Immunology       Date:  1988-09       Impact factor: 7.397

5.  The T-cell activating protein (TAP) is up-regulated by endogenous IFN-gamma in activated T cells.

Authors:  F J Dumont; R G Palfree; P A Fisher
Journal:  Immunology       Date:  1988-06       Impact factor: 7.397

6.  Phenotypic properties, interleukin 2 production, and developmental origin of a "mature" subpopulation of Lyt-2- L3T4- mouse thymocytes.

Authors:  R Ceredig; F Lynch; P Newman
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

Review 7.  Cell-mediated immunity in virus infections of the central nervous system.

Authors:  P C Doherty
Journal:  Ann N Y Acad Sci       Date:  1988       Impact factor: 5.691
  7 in total

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