| Literature DB >> 31021186 |
Abstract
Genome editing with engineered nucleases, a powerful tool for understanding biological function and revealing causality, was built in a joint effort by academia and industry in 1994-2010. Use of CRISPR-Cas9 is the most recent (2013-), and facile, implementation of the resulting editing toolbox. Principles and methods of genome editing from the pre-CRISPR era remain relevant and continue to be useful.Year: 2018 PMID: 31021186 DOI: 10.1089/crispr.2018.29007.fyu
Source DB: PubMed Journal: CRISPR J ISSN: 2573-1599