Literature DB >> 31019439

Early-Onset Breast Cancer: Effect of Diagnosis and Therapy on Fertility Concerns, Endocrine System, and Sexuality of Young Mothers in Germany.

Telja Pursche1, Julia Bauer2, Friederike Hammersen3, Achim Rody1, Annika Waldmann3,4, Dorothea Fischer5.   

Abstract

BACKGROUND: The purpose of this study was to analyze the effect of breast cancer therapy on fertility concerns and sexuality of young mothers with breast cancer in Germany.
METHODS: During a mother-child rehabilitation program, 1,191 young mothers with locoregional primary breast cancer, treated between 2006 and 2014, were recruited. Data included sociodemographic data, TNM stage, tumor biology, therapies, and patient-reported outcomes such as sexuality and fertility concerns.
RESULTS: The mean age at diagnosis was 40 years. Approximately a quarter of the patients stated that family planning had not been completed at the time of diagnosis. Nearly half of all patients had been informed as to how treatment could affect fertility, but counseling at a specialized fertility center was offered to only 13%. Of all patients, 4% took a consultation and 2% underwent fertility preservation procedures.
CONCLUSION: Our study indicates that only a minority of patients is referred to fertility centers although family planning is incomplete at the time of diagnosis in about 25% of young women with breast cancer. Thus, these patients should not only be informed about the effects of treatment on fertility and sexuality, but should be referred to a fertility center.

Entities:  

Keywords:  Breast cancer; Family planning; Fertility; Sexuality

Year:  2018        PMID: 31019439      PMCID: PMC6465684          DOI: 10.1159/000488795

Source DB:  PubMed          Journal:  Breast Care (Basel)        ISSN: 1661-3791            Impact factor:   2.860


  21 in total

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Journal:  Eur J Cancer       Date:  2001-07       Impact factor: 9.162

Review 2.  Pregnancy after breast cancer. A comprehensive review.

Authors:  Eelco de Bree; Antonios Makrigiannakis; John Askoxylakis; John Melissas; Dimitris D Tsiftsis
Journal:  J Surg Oncol       Date:  2010-05-01       Impact factor: 3.454

3.  Sexual desire and satisfaction in sexual life affecting factors in breast cancer survivors after mastectomy.

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Journal:  J Psychosoc Oncol       Date:  2009

4.  Facilitating reproductive choices: the impact of health services on the experiences of young women with breast cancer.

Authors:  Rebecca J Lee; Ann Wakefield; Sharon Foy; Sacha J Howell; Andrew M Wardley; Anne C Armstrong
Journal:  Psychooncology       Date:  2010-09-02       Impact factor: 3.894

Review 5.  Reproduction beyond cancer: a message of hope for young women.

Authors:  Theodoros Maltaris; Daniel Boehm; Ralf Dittrich; Rudolf Seufert; Heinz Koelbl
Journal:  Gynecol Oncol       Date:  2006-09-25       Impact factor: 5.482

6.  Sexual functioning in long-term breast cancer survivors treated with adjuvant chemotherapy.

Authors:  Jo A Broeckel; Christina L Thors; Paul B Jacobsen; Margaret Small; Charles E Cox
Journal:  Breast Cancer Res Treat       Date:  2002-10       Impact factor: 4.872

7.  Quality of life over 5 years in women with breast cancer after breast-conserving therapy versus mastectomy: a population-based study.

Authors:  Volker Arndt; Christa Stegmaier; Hartwig Ziegler; Hermann Brenner
Journal:  J Cancer Res Clin Oncol       Date:  2008-05-27       Impact factor: 4.553

Review 8.  Psychological aspects of fertility preservation in men and women affected by cancer and other life-threatening diseases.

Authors:  Sibil Tschudin; Johannes Bitzer
Journal:  Hum Reprod Update       Date:  2009-05-10       Impact factor: 15.610

9.  Quality of life following breast-conserving therapy or mastectomy: results of a 5-year prospective study.

Authors:  Jutta Engel; Jacqueline Kerr; Anne Schlesinger-Raab; Hansjörg Sauer; Dieter Hölzel
Journal:  Breast J       Date:  2004 May-Jun       Impact factor: 2.431

10.  The population-based oncological health care study OVIS - recruitment of the patients and analysis of the non-participants.

Authors:  Ron Pritzkuleit; Annika Waldmann; Heiner Raspe; Alexander Katalinic
Journal:  BMC Cancer       Date:  2008-10-27       Impact factor: 4.430

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  2 in total

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Authors:  Merri Iddrisu; Lydia Aziato; Florence Dedey
Journal:  BMC Psychiatry       Date:  2020-07-06       Impact factor: 3.630

2.  Amenorrhea, fertility preservation, and counseling among young women treated with anthracyclines and taxanes for early-stage breast cancer, a retrospective study.

Authors:  Hikmat N Abdel-Razeq; Razan A Mansour; Khawla S Ammar; Rashid H Abdel-Razeq; Hadil Y Zureigat; Lina M Yousef; Omar A Shahin
Journal:  Medicine (Baltimore)       Date:  2020-03       Impact factor: 1.817

  2 in total

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