| Literature DB >> 31016721 |
Shauna M Quinn1, Mathilde Raverdeau1, Aoife M McGinley1, Kingston H G Mills1.
Abstract
Infection with helminths can protect against the development of autoimmune diseases and this has been associated with induction of anti-inflammatory innate immune responses and Tregs. Here, we demonstrate that helminth-derived products can directly target T cells, especially IL-17-secreting γδ T cells that play a key pathogenic role in CNS autoimmune disease.Entities:
Keywords: Experimental autoimmune encephalomyelitis; Fasciola hepatica; IL-17; Th17; γδ T cell
Mesh：
Substances：
Year: 2019 PMID： 31016721 DOI： 10.1002/eji.201948147
Source DB: PubMed Journal: Eur J Immunol ISSN： 0014-2980 Impact factor: 5.532