Literature DB >> 31015904

Diversity of PEGylation methods of liposomes and their influence on RNA delivery.

A S Nosova1, O O Koloskova1, A A Nikonova1,2, V A Simonova3, V V Smirnov1,3, D Kudlay1, M R Khaitov1.   

Abstract

Gene therapy is a promising approach for personalized medicine, but its application in humans requires development of efficient and safe vehicles. PEGylated liposomes are some of the most suitable delivery systems for nucleic acids because of their stability under physiological conditions and prolonged circulation time, compared to conventional and other types of "stealth" liposomes. In vitro/in vivo activity of PEGylated liposomes is highly dependent on PEG motif abundance. The process of "stealth" coverage formation is a very important parameter for efficient transfection assays and further fate determination of the PEG layer after tissue penetration. In this review, we discuss the latest methods of PEGylated liposome preparation.

Entities:  

Year:  2019        PMID： 31015904      PMCID： PMC6457174          DOI： 10.1039/c8md00515j

Source DB:  PubMed          Journal:  Medchemcomm        ISSN： 2040-2503            Impact factor:   3.597


  14 in total

Review 1.  Liposomal delivery of CRISPR/Cas9.

Authors:  Shuai Zhen; Xu Li
Journal:  Cancer Gene Ther       Date:  2019-11-02       Impact factor: 5.987

2.  Fatty Acid Synthase (FASN) siRNA-Encapsulated-Her-2 Targeted Fab'-Immunoliposomes for Gene Silencing in Breast Cancer Cells.

Authors:  Arif Khan; Masood A Khan; Ahmed N Aljarbou; Yousef H Aldebasi; Khaled S Allemailem; Mohammed A Alsahli; Shamshir Khan; Abdulmohsen M Alruwetei
Journal:  Int J Nanomedicine       Date:  2020-08-05

Review 3.  Understanding the Role and Impact of Poly (Ethylene Glycol) (PEG) on Nanoparticle Formulation: Implications for COVID-19 Vaccines.

Authors:  Esperanza Padín-González; Pearl Lancaster; Massimo Bottini; Paolo Gasco; Lang Tran; Bengt Fadeel; Terence Wilkins; Marco P Monopoli
Journal:  Front Bioeng Biotechnol       Date:  2022-06-07

4.  Computational and Experimental Approaches to Investigate Lipid Nanoparticles as Drug and Gene Delivery Systems.

Authors:  Chun Chan; Shi Du; Yizhou Dong; Xiaolin Cheng
Journal:  Curr Top Med Chem       Date:  2021       Impact factor: 3.295

Review 5.  Strategies to deliver RNA by nanoparticles for therapeutic potential.

Authors:  Alysia Cox; Siyoung A Lim; Eun Ji Chung
Journal:  Mol Aspects Med       Date:  2021-08-05

Review 6.  Biocompatibility of nanomaterials and their immunological properties.

Authors:  Themis R Kyriakides; Arindam Raj; Tiffany H Tseng; Hugh Xiao; Ryan Nguyen; Farrah S Mohammed; Saiti Halder; Mengqing Xu; Michelle J Wu; Shuozhen Bao; Wendy C Sheu
Journal:  Biomed Mater       Date:  2021-03-11       Impact factor: 3.715

Review 7.  Protein-Based Nanohydrogels for Bioactive Delivery.

Authors:  Subhash Chander; Giriraj T Kulkarni; Neerupma Dhiman; Harsha Kharkwal
Journal:  Front Chem       Date:  2021-07-09       Impact factor: 5.221

8.  Designing siRNA/chitosan-methacrylate complex nanolipogel for prolonged gene silencing effects.

Authors:  Ye Cao; Yang Fei Tan; Yee Shan Wong; Muhammad Aminuddin; Bhuthalingam Ramya; Melvin Wen Jie Liew; Jiaxin Liu; Subbu S Venkatraman
Journal:  Sci Rep       Date:  2022-03-03       Impact factor: 4.379

9.  Trojan horse treatment based on PEG-coated extracellular vesicles to deliver doxorubicin to melanoma in vitro and in vivo.

Authors:  Laura Patras; Aura Elena Ionescu; Cristian Munteanu; Renata Hajdu; Andreea Kosa; Alina Porfire; Emilia Licarete; Valentin Florian Rauca; Alina Sesarman; Lavinia Luput; Paul Bulzu; Paul Chiroi; Rares Andrei Tranca; Marta-Szilvia Meszaros; Giorgiana Negrea; Lucian Barbu-Tudoran; Monica Potara; Stefan Szedlacsek; Manuela Banciu
Journal:  Cancer Biol Ther       Date:  2021-12-29       Impact factor: 4.742

10.  Lipoplexes to Deliver Oligonucleotides in Gram-Positive and Gram-Negative Bacteria: Towards Treatment of Blood Infections.

Authors:  Sara Pereira; Rita Sobral Santos; Luís Moreira; Nuno Guimarães; Mariana Gomes; Heyang Zhang; Katrien Remaut; Kevin Braeckmans; Stefaan De Smedt; Nuno Filipe Azevedo
Journal:  Pharmaceutics       Date:  2021-06-29       Impact factor: 6.321
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