Literature DB >> 31015119

Estimating the cost of radiotherapy for 5-year local control and overall survival benefit.

Vikneswary Batumalai1, Karen Wong2, Jesmin Shafiq3, Timothy P Hanna4, Gabriel Gabriel3, Julia Heberle5, Ivan Koprivic5, Nasreen Kaadan6, Odette King7, Thomas Tran7, Lynette Cassapi8, Dion Forstner9, Geoff P Delaney2, Michael Barton2.   

Abstract

BACKGROUND AND
PURPOSE: Escalating health care costs have led to greater efforts directed at measuring the cost and benefits of medical treatments. The aim of this study was to estimate the costs of 5-year local control and overall survival benefits of radiotherapy for the cancer population in Australia.
MATERIALS AND METHODS: The local control and overall survival benefits of radiotherapy at 5-years and optimal number of fractions per course have been estimated for 26 tumour sites for which radiotherapy is indicated. For this study, a hybrid approach that merges features from activity based costing (ABC) and relative value units costing (RVU) were used to provide cost estimates. ABC methodology was used to allocate costs to all radiotherapy activities associated with each patient's treatment course, while the RVUs represent the cost of each radiotherapy activity relative to the average cost of all activities and were used to achieve a weighted cost allocation. A patient's journey for the financial year was constructed by consolidating all the radiotherapy activities and their associated costs, and the average cost per activity (fraction) was determined. The cost of radiotherapy per 5-year overall survival and local control was then estimated.
RESULTS: The estimated population 5-year local control and overall survival benefits of radiotherapy for all cancer were 23% and 6%, respectively. The optimal number of fractions per treatment course if guidelines were followed was 19.4 fractions. The average cost per fraction for all cancer was AU$276. The estimated cost of radiotherapy was AU$23,585 per 5-year local control and AU$86,480 per 5-year overall survival (equivalent to 5 life years) for all cancer.
CONCLUSION: The cost of AU$86,480 per 5-year overall survival would translate to AU$17,296 1-year overall survival. Therefore, the cost of radiotherapy is inexpensive if delivered optimally. Policy implications from this study include knowledge about cost to deliver radiotherapy to allow one to quantify the expected benefit at a population level. Crown
Copyright © 2019. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Activity based costing; Cost benefit; Local control; Overall survival; Radiotherapy; Relative value unit

Mesh:

Year:  2019        PMID: 31015119     DOI: 10.1016/j.radonc.2019.04.011

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  5 in total

Review 1.  Integrated MRI-guided radiotherapy - opportunities and challenges.

Authors:  Paul J Keall; Caterina Brighi; Carri Glide-Hurst; Gary Liney; Paul Z Y Liu; Suzanne Lydiard; Chiara Paganelli; Trang Pham; Shanshan Shan; Alison C Tree; Uulke A van der Heide; David E J Waddington; Brendan Whelan
Journal:  Nat Rev Clin Oncol       Date:  2022-04-19       Impact factor: 65.011

2.  Variation in the use of radiotherapy fractionation for breast cancer: Survival outcome and cost implications.

Authors:  Vikneswary Batumalai; Geoff P Delaney; Joseph Descallar; Gabriel Gabriel; Karen Wong; Jesmin Shafiq; Michael Barton
Journal:  Radiother Oncol       Date:  2020-07-25       Impact factor: 6.280

3.  Implementation of a DVH Registry to provide constraints and continuous quality monitoring for pediatric CSI treatment planning.

Authors:  Esteban Sepulveda; Haley Patrick; Carolyn R Freeman; John Kildea
Journal:  J Appl Clin Med Phys       Date:  2020-12-14       Impact factor: 2.102

Review 4.  Matrices and Affinity Ligands for Antibody Purification and Corresponding Applications in Radiotherapy.

Authors:  Aiying Xue; Saijun Fan
Journal:  Biomolecules       Date:  2022-06-12

5.  The challenge of sustainability in healthcare systems: cost of radiotherapy in the last month of life in an Italian cancer center.

Authors:  Romina Rossi; Valentina Danesi; Ilaria Massa; William Balzi; Antonino Romeo; Flavia Foca; Oriana Nanni; Marco Maltoni; Mattia Altini
Journal:  Support Care Cancer       Date:  2020-09-28       Impact factor: 3.603

  5 in total

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