Gowtham Jonna1, Anthony B Daniels2. 1. Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville, Tennessee. 2. Department of Ophthalmology and Visual Sciences, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: anthony.b.daniels@gmail.com.
Abstract
PURPOSE: To characterize the enhanced depth imaging (EDI) OCT features of ultrasonographically flat choroidal nevi. DESIGN: Retrospective observational study. PARTICIPANTS: Patients with ultrasonographically flat choroidal nevi identified over a 3-year period. METHODS: Comprehensive eye examinations and multimodal imaging were performed every 6 to 12 months. MAIN OUTCOME MEASURES: Lesion thickness and features, EDI-OCT findings. RESULTS: A total of 102 nevi (98 patients) were included. Median follow-up was 9 months (range 0-144 months) and 1 to 8 (mean 2.1) OCTs were performed. On OCT, nevi were classified into 5 subtypes: 3.2% were "not visible," 37.2% had "hyperreflectivity confined within normal choroidal thickness," 16.0% had characteristic anteriorly bowed hyperreflectivity with "discrete" borders and cascading edges, 14.9% were "flat with posterior bowing," and 28.7% were "elevated." One nevus of the "elevated" type demonstrated clinically insignificant growth (<10% in thickness) after 22 months of follow-up. CONCLUSIONS: Five distinct EDI-OCT patterns of choroidal nevi seemed flat on ultrasonography, and many demonstrated thickness and elevation not measurable on B-scan ultrasonography. Lesion thickness can be measured using EDI-OCT.
PURPOSE: To characterize the enhanced depth imaging (EDI) OCT features of ultrasonographically flat choroidal nevi. DESIGN: Retrospective observational study. PARTICIPANTS: Patients with ultrasonographically flat choroidal nevi identified over a 3-year period. METHODS: Comprehensive eye examinations and multimodal imaging were performed every 6 to 12 months. MAIN OUTCOME MEASURES: Lesion thickness and features, EDI-OCT findings. RESULTS: A total of 102 nevi (98 patients) were included. Median follow-up was 9 months (range 0-144 months) and 1 to 8 (mean 2.1) OCTs were performed. On OCT, nevi were classified into 5 subtypes: 3.2% were "not visible," 37.2% had "hyperreflectivity confined within normal choroidal thickness," 16.0% had characteristic anteriorly bowed hyperreflectivity with "discrete" borders and cascading edges, 14.9% were "flat with posterior bowing," and 28.7% were "elevated." One nevus of the "elevated" type demonstrated clinically insignificant growth (<10% in thickness) after 22 months of follow-up. CONCLUSIONS: Five distinct EDI-OCT patterns of choroidal nevi seemed flat on ultrasonography, and many demonstrated thickness and elevation not measurable on B-scan ultrasonography. Lesion thickness can be measured using EDI-OCT.
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Authors: Carol L Shields; Minoru Furuta; Archana Thangappan; Saya Nagori; Arman Mashayekhi; David R Lally; Cecilia C Kelly; Danielle S Rudich; Anand V Nagori; Oojwala A Wakade; Sonul Mehta; Lauren Forte; Andrew Long; Elaina F Dellacava; Bonnie Kaplan; Jerry A Shields Journal: Arch Ophthalmol Date: 2009-08