Literature DB >> 31013116

SPLUNC1 Loses Its Antimicrobial Activity in Acidic Cystic Fibrosis Airway Secretions.

Saira Ahmad1, Rodney C Gilmore1, Neil E Alexis1, Robert Tarran1.   

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Year:  2019        PMID： 31013116      PMCID： PMC6727152          DOI： 10.1164/rccm.201812-2303LE

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  9 in total

1.  Phenotypes of Rapid Cystic Fibrosis Lung Disease Progression during Adolescence and Young Adulthood.

Authors:  Rhonda D Szczesniak; Dan Li; Weiji Su; Cole Brokamp; John Pestian; Michael Seid; John P Clancy
Journal:  Am J Respir Crit Care Med       Date:  2017-08-15       Impact factor: 21.405

2.  pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37.

Authors:  Mahmoud H Abou Alaiwa; Leah R Reznikov; Nicholas D Gansemer; Kelsey A Sheets; Alexander R Horswill; David A Stoltz; Joseph Zabner; Michael J Welsh
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-15       Impact factor: 11.205

3.  Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis.

Authors:  Kathryn A Ramsey; Sarath Ranganathan; Judy Park; Billy Skoric; Anne-Marie Adams; Shannon J Simpson; Roy M Robins-Browne; Peter J Franklin; Nick H de Klerk; Peter D Sly; Steve M Stick; Graham L Hall
Journal:  Am J Respir Crit Care Med       Date:  2014-11-15       Impact factor: 21.405

4.  Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways.

Authors:  Alaina L Garland; William G Walton; Raymond D Coakley; Chong D Tan; Rodney C Gilmore; Carey A Hobbs; Ashutosh Tripathy; Lucy A Clunes; Sompop Bencharit; M Jackson Stutts; Laurie Betts; Matthew R Redinbo; Robert Tarran
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-16       Impact factor: 11.205

5.  Abnormal surface liquid pH regulation by cultured cystic fibrosis bronchial epithelium.

Authors:  Raymond D Coakley; Barbara R Grubb; Anthony M Paradiso; John T Gatzy; Larry G Johnson; Sylvia M Kreda; Wanda K O'Neal; Richard C Boucher
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-10       Impact factor: 11.205

6.  Short Palate, Lung, and Nasal Epithelial Clone 1 Has Antimicrobial and Antibiofilm Activities against the Burkholderia cepacia Complex.

Authors:  Saira Ahmad; Jean Tyrrell; William G Walton; Ashutosh Tripathy; Matthew R Redinbo; Robert Tarran
Journal:  Antimicrob Agents Chemother       Date:  2016-09-23       Impact factor: 5.191

7.  SPLUNC1 degradation by the cystic fibrosis mucosal environment drives airway surface liquid dehydration.

Authors:  Megan J Webster; Boris Reidel; Chong D Tan; Arunava Ghosh; Neil E Alexis; Scott H Donaldson; Mehmet Kesimer; Carla M P Ribeiro; Robert Tarran
Journal:  Eur Respir J       Date:  2018-10-04       Impact factor: 16.671

8.  Airway surface liquid pH is not acidic in children with cystic fibrosis.

Authors:  André Schultz; Ramaa Puvvadi; Sergey M Borisov; Nicole C Shaw; Ingo Klimant; Luke J Berry; Samuel T Montgomery; Thien Nguyen; Silvia M Kreda; Anthony Kicic; Peter B Noble; Brian Button; Stephen M Stick
Journal:  Nat Commun       Date:  2017-11-10       Impact factor: 14.919

9.  Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung.

Authors:  Alejandro A Pezzulo; Xiao Xiao Tang; Mark J Hoegger; Mahmoud H Abou Alaiwa; Shyam Ramachandran; Thomas O Moninger; Phillip H Karp; Christine L Wohlford-Lenane; Henk P Haagsman; Martin van Eijk; Botond Bánfi; Alexander R Horswill; David A Stoltz; Paul B McCray; Michael J Welsh; Joseph Zabner
Journal:  Nature       Date:  2012-07-04       Impact factor: 49.962
  9 in total
  4 in total

1.  A SPLUNC1 Peptidomimetic Inhibits Orai1 and Reduces Inflammation in a Murine Allergic Asthma Model.

Authors:  Joe A Wrennall; Saira Ahmad; Erin N Worthington; Tongde Wu; Alexandra S Goriounova; Alexis S Voeller; Ian E Stewart; Arunava Ghosh; Krzysztof Krajewski; Steven L Tilley; Anthony J Hickey; M Flori Sassano; Robert Tarran
Journal:  Am J Respir Cell Mol Biol       Date:  2022-03       Impact factor: 6.914

2.  The SPLUNC1-βENaC complex prevents Burkholderia cenocepacia invasion in normal airway epithelia.

Authors:  Saira Ahmad; Christine Seul Ki Kim; Robert Tarran
Journal:  Respir Res       Date:  2020-07-17

Review 3.  CFTR Protein: Not Just a Chloride Channel?

Authors:  Laurence S Hanssens; Jean Duchateau; Georges J Casimir
Journal:  Cells       Date:  2021-10-22       Impact factor: 6.600

Review 4.  Mechanisms of Epithelial Immunity Evasion by Respiratory Bacterial Pathogens.

Authors:  Lokesh Sharma; Jingjing Feng; Clemente J Britto; Charles S Dela Cruz
Journal:  Front Immunol       Date:  2020-02-11       Impact factor: 7.561
  4 in total

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