Literature DB >> 31012227

Sex differences in the treatment and outcomes of patients hospitalized with ST-elevation myocardial infarction.

Edward L Hannan1, Yifeng Wu1, Jacqueline Tamis-Holland2, Alice K Jacobs3, Peter B Berger4, Frederick S K Ling5, Gary Walford6, Ferdinand J Venditti7, Spencer B King8.   

Abstract

OBJECTIVES: To compare mortality for women and men hospitalized with ST-elevation myocardial infarction (STEMI) by age and revascularization status.
BACKGROUND: There is little information on the mortality of men and women not undergoing revascularization, and the impact of age on relative male-female mortality needs to be revisited. METHODS AND
RESULTS: An observational database of 23,809 patients with STEMI presenting at nonfederal New York State hospitals between 2013 and 2015 was used to compare risk-adjusted inhospital/30-day mortality for women and men and to explore the impact of age on those differences. Women had significantly higher mortality than men overall (adjusted odds ratio [AOR] = 1.15, 95% CI [1.04, 1.28]), and among patients aged 65 and older. Women had lower revascularization rates in general (AOR = 0.64 [0.59, 0.69]) and for all age groups. Among revascularized STEMI patients, women overall (AOR = 1.30 [1.10, 1.53]) and over 65 had higher mortality than men. Among patients not revascularized, women between the ages of 45 and 64 had lower mortality (AOR = 0.68 [0.48, 0.97]).
CONCLUSIONS: Women with STEMI, and especially older women, had higher inhospital/30-day mortality rates than their male counterparts. Women had higher mortality among revascularized patients, but not among patients who were not revascularized.
© 2019 Wiley Periodicals, Inc.

Entities:  

Keywords:  ST-elevation myocardial infarction; mortality; myocardial infarction; revascularization; sex differences

Year:  2019        PMID: 31012227     DOI: 10.1002/ccd.28286

Source DB:  PubMed          Journal:  Catheter Cardiovasc Interv        ISSN: 1522-1946            Impact factor:   2.692


  5 in total

1.  Implicit bias in healthcare: clinical practice, research and decision making.

Authors:  Dipesh P Gopal; Ula Chetty; Patrick O'Donnell; Camille Gajria; Jodie Blackadder-Weinstein
Journal:  Future Healthc J       Date:  2021-03

2.  Outcomes of ST-elevation myocardial infarction by age and sex in a low-income urban community: The Montefiore STEMI Registry.

Authors:  Anna E Bortnick; Muhammad Shahid; Sanyog G Shitole; Michael Park; Anna Broder; Carlos J Rodriguez; James Scheuer; Robert Faillace; Jorge R Kizer
Journal:  Clin Cardiol       Date:  2020-07-28       Impact factor: 2.882

3.  The Effect of Periprocedural Clinical Factors Related to the Course of STEMI in Men and Women Based on the National Registry of Invasive Cardiology Procedures (ORPKI) between 2014 and 2019.

Authors:  Janusz Sielski; Karol Kaziród-Wolski; Karolina Jurys; Paweł Wałek; Zbigniew Siudak
Journal:  J Clin Med       Date:  2021-12-06       Impact factor: 4.241

4.  Contemporary sex differences in mortality among patients with ST-segment elevation myocardial infarction: a systematic review and meta-analysis.

Authors:  Ziwei Xi; Hong Qiu; Tingting Guo; Yong Wang; Jianan Li; Yang Li; Jianfeng Zheng; R Gao
Journal:  BMJ Open       Date:  2022-03-09       Impact factor: 2.692

5.  Treatment Effect of Percutaneous Coronary Intervention in Men Versus Women With ST-Segment-Elevation Myocardial Infarction.

Authors:  Samian Sulaiman; Akram Kawsara; Mohamed O Mohamed; Harriette G C Van Spall; Nadia Sutton; David R Holmes; Mamas A Mamas; Mohamad Alkhouli
Journal:  J Am Heart Assoc       Date:  2021-09-17       Impact factor: 5.501

  5 in total

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