Literature DB >> 31012013

The New Plant Expression System for the Development of Vaccines against Papillomaviruses.

R K Salyaev1, N I Rekoslavskaya2,3, A S Stolbikov4.   

Abstract

To enhance the synthesis of antigenic envelope proteins L1 of high-grade papillomavirus types HPV16, HPV18, HPV31, and HPV45, the sequence of the gene encoding the cucumber mosaic virus replicase (RdRP CMV) was inserted into the genetic construct. This made it possible to increase the production of these antigenic proteins to 25-27 μg/mg total soluble protein.

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Year:  2019        PMID： 31012013     DOI： 10.1134/S1607672919010150

Source DB:  PubMed          Journal:  Dokl Biochem Biophys        ISSN： 1607-6729            Impact factor:   0.788


  1 in total

1.  The Antiproliferative Effect of the "Early" Protein E2 of Papillomavirus HPV16 on Testis Tumors of Mice Induced by the Injection of HeLa Cells.

Authors:  R K Salyaev; N I Rekoslavskaya; A S Stolbikov
Journal:  Dokl Biochem Biophys       Date:  2019-11-25       Impact factor: 0.788
  1 in total

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