Literature DB >> 31010863

Validation and Application of an HPLC-DAD Method for Routine Therapeutic Drug Monitoring of Ceftobiprole.

Benjamin Lima1, Sandra Bodeau1,2, Marie-Charlotte Quinton1, Cyril Leven3, Anne-Sophie Lemaire-Hurtel1, Youssef Bennis4,2.   

Abstract

Ceftobiprole is a fifth-generation cephalosporin approved for the treatment of pneumonia, with a broad antibacterial spectrum, including potent activity against methicillin-resistant Staphylococcus aureus As for the other cephalosporins, high pharmacokinetic variability and concentration-dependent neurotoxicity are expected. We describe here the first simple and rapid analytical method intended for ceftobiprole serum concentration monitoring. We report the data of 5 patients treated with ceftobiprole, among who 2 developed reversible neurological disorders with high ceftobiprole serum concentration.
Copyright © 2019 American Society for Microbiology.

Entities:  

Keywords:  MRSA; cephalosporin; neurotoxicity; pneumonia; therapeutic drug monitoring

Year:  2019        PMID： 31010863      PMCID： PMC6591631          DOI： 10.1128/AAC.00515-19

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Single-dose pharmacokinetics and safety of a novel broad-spectrum cephalosporin (BAL5788) in healthy volunteers.

Authors:  Anne Schmitt-Hoffmann; Brigitte Roos; Michael Schleimer; Jill Sauer; Anthony Man; Norman Nashed; Thomas Brown; Antonio Perez; Erhard Weidekamm; Péter Kovács
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

2.  Analysis of 12 beta-lactam antibiotics in human plasma by HPLC with ultraviolet detection.

Authors:  Brett C McWhinney; Steven C Wallis; Tara Hillister; Jason A Roberts; Jeffrey Lipman; Jacobus P J Ungerer
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2010-05-24       Impact factor: 3.205

3.  Ceftobiprole activity against over 60,000 clinical bacterial pathogens isolated in Europe, Turkey, and Israel from 2005 to 2010.

Authors:  David J Farrell; Robert K Flamm; Helio S Sader; Ronald N Jones
Journal:  Antimicrob Agents Chemother       Date:  2014-04-28       Impact factor: 5.191

4.  Simultaneous determination of five beta-lactam antibiotics (cefepim, ceftazidim, cefuroxim, meropenem and piperacillin) in human plasma by high-performance liquid chromatography with ultraviolet detection.

Authors:  Raphaël Denooz; Corinne Charlier
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2008-02-02       Impact factor: 3.205

5.  In vitro activity profile of ceftobiprole, an anti-MRSA cephalosporin, against recent gram-positive and gram-negative isolates of European origin.

Authors:  Chris M Pillar; Mohana K Aranza; Dineshchandra Shah; Daniel F Sahm
Journal:  J Antimicrob Chemother       Date:  2008-01-23       Impact factor: 5.790

6.  Serious central nervous system side effects of cephalosporins: A national analysis of serious reports registered in the French Pharmacovigilance Database.

Authors:  C Lacroix; F Kheloufi; F Montastruc; Y Bennis; V Pizzoglio; J Micallef
Journal:  J Neurol Sci       Date:  2019-01-16       Impact factor: 3.181

7.  Multiple-dose pharmacokinetics and safety of a novel broad-spectrum cephalosporin (BAL5788) in healthy volunteers.

Authors:  Anne Schmitt-Hoffmann; Lars Nyman; Brigitte Roos; Michael Schleimer; Jill Sauer; Norman Nashed; Thomas Brown; Anthony Man; Erhard Weidekamm
Journal:  Antimicrob Agents Chemother       Date:  2004-07       Impact factor: 5.191

Review 8.  Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams.

Authors:  Joao Gonçalves-Pereira; Pedro Póvoa
Journal:  Crit Care       Date:  2011-09-13       Impact factor: 9.097

Review 9.  Pharmacokinetics and Dosing of Ceftobiprole Medocaril for the Treatment of Hospital- and Community-Acquired Pneumonia in Different Patient Populations.

Authors:  Antonio Torres; Johan Willem Mouton; Federico Pea
Journal:  Clin Pharmacokinet       Date:  2016-12       Impact factor: 6.447

Review 10.  Optimization of the treatment with beta-lactam antibiotics in critically ill patients-guidelines from the French Society of Pharmacology and Therapeutics (Société Française de Pharmacologie et Thérapeutique-SFPT) and the French Society of Anaesthesia and Intensive Care Medicine (Société Française d'Anesthésie et Réanimation-SFAR).

Authors:  Romain Guilhaumou; Sihem Benaboud; Youssef Bennis; Claire Dahyot-Fizelier; Eric Dailly; Peggy Gandia; Sylvain Goutelle; Sandrine Lefeuvre; Nicolas Mongardon; Claire Roger; Julien Scala-Bertola; Florian Lemaitre; Marc Garnier
Journal:  Crit Care       Date:  2019-03-29       Impact factor: 9.097
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  1 in total

1.  Clinical Response and Hospital Costs of Therapeutic Drug Monitoring for Vancomycin in Elderly Patients.

Authors:  Yun Kim; Soohyun Kim; Jinsook Park; Howard Lee
Journal:  J Pers Med       Date:  2022-01-26
  1 in total

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