Literature DB >> 31010465

The Aging Lung and Idiopathic Pulmonary Fibrosis.

Swati Gulati1, Victor J Thannickal2.   

Abstract

Idiopathic pulmonary fibrosis (IPF) is one of many clinical syndromes that are associated with aging, and is increasing in both incidence and prevalence with the rapid rise in aging populations world-wide. There is accumulating data on how the biology of aging may influence the susceptibility to lung fibrosis in the elderly. In this review, we explore some of the known "hallmarks of aging," including telomere attrition, genomic instability, epigenetic alterations, loss of proteostasis, cellular senescence and mitochondrial dysfunction in the pathobiology of IPF. Additionally, we discuss age-associated alterations in extracellular matrix that may contribute to the development and/or progression of IPF.
Copyright © 2019. Published by Elsevier Inc.

Entities:  

Keywords:  Aging; Fibrosis; Idiopathic pulmonary fibrosis

Year:  2019        PMID： 31010465     DOI： 10.1016/j.amjms.2019.02.008

Source DB:  PubMed          Journal:  Am J Med Sci        ISSN： 0002-9629            Impact factor:   2.378


  25 in total

1.  Age-dependent regulation of cell-mediated collagen turnover.

Authors:  Michael J Podolsky; Christopher D Yang; Carlos Lizama Valenzuela; Ritwik Datta; Steven K Huang; Stephen L Nishimura; Sarah L Dallas; Paul J Wolters; Claude Jourdan Le Saux; Kamran Atabai
Journal:  JCI Insight       Date:  2020-05-21

2.  Glycine max (soy) based diet improves antioxidant defenses and prevents cell death in cadmium intoxicated lungs.

Authors:  Gabriel Giezi Boldrini; Glenda Martín Molinero; María Verónica Pérez Chaca; María Eugenia Ciminari; Franco Moyano; Maria Evelyn Córdoba; Gisela Pennacchio; Mariel Fanelli; Silvina Mónica Álvarez; Nidia Noemí Gómez
Journal:  Biometals       Date:  2022-01-17       Impact factor: 2.949

3.  The profibrotic and senescence phenotype of old lung fibroblasts is reversed or ameliorated by genetic and pharmacological manipulation of Slc7a11 expression.

Authors:  Jeffrey D Ritzenthaler; Edilson Torres-Gonzalez; Yuxuan Zheng; Igor N Zelko; Victor van Berkel; David R Nunley; Biniam Kidane; Andrew J Halayko; Ross Summer; Walter H Watson; Jesse Roman
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2022-01-05       Impact factor: 5.464

4.  Elevated Expression of Growth Differentiation Factor-15 Is Associated With Acute Exacerbation of Idiopathic Pulmonary Fibrosis.

Authors:  Mengshu Cao; Lina Gu; Lili Guo; Mengying Liu; Tianzhen Wang; Ji Zhang; Huizhe Zhang; Yufeng Zhang; Yanchen Shi; Yichao Zhao; Xiaohua Qiu; Xianhua Gui; Miao Ma; Yaqiong Tian; Xiaoqin Liu; Fanqing Meng; Yonglong Xiao; Lingyun Sun
Journal:  Front Immunol       Date:  2022-06-15       Impact factor: 8.786

Review 5.  Insights into the Pathogenesis of Pulmonary Fibrosis from Genetic Diseases.

Authors:  Joanna Y Wang; Lisa R Young
Journal:  Am J Respir Cell Mol Biol       Date:  2022-07       Impact factor: 7.748

6.  Frataxin deficiency promotes endothelial senescence in pulmonary hypertension.

Authors:  Miranda K Culley; Jingsi Zhao; Yi Yin Tai; Ying Tang; Dror Perk; Vinny Negi; Qiujun Yu; Chen-Shan C Woodcock; Adam Handen; Gil Speyer; Seungchan Kim; Yen-Chun Lai; Taijyu Satoh; Annie Mm Watson; Yassmin Al Aaraj; John Sembrat; Mauricio Rojas; Dmitry Goncharov; Elena A Goncharova; Omar F Khan; Daniel G Anderson; James E Dahlman; Aditi U Gurkar; Robert Lafyatis; Ahmed U Fayyaz; Margaret M Redfield; Mark T Gladwin; Marlene Rabinovitch; Mingxia Gu; Thomas Bertero; Stephen Y Chan
Journal:  J Clin Invest       Date:  2021-06-01       Impact factor: 14.808

7.  Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis.

Authors:  Yoshihiko Kobayashi; Aleksandra Tata; Arvind Konkimalla; Hiroaki Katsura; Rebecca F Lee; Jianhong Ou; Nicholas E Banovich; Jonathan A Kropski; Purushothama Rao Tata
Journal:  Nat Cell Biol       Date:  2020-07-13       Impact factor: 28.824

Review 8.  Shared and distinct mechanisms of fibrosis.

Authors:  Jörg H W Distler; Andrea-Hermina Györfi; Meera Ramanujam; Michael L Whitfield; Melanie Königshoff; Robert Lafyatis
Journal:  Nat Rev Rheumatol       Date:  2019-11-11       Impact factor: 20.543

9.  The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality.

Authors:  Jason L Sanders; Rachel K Putman; Josée Dupuis; Hanfei Xu; Joanne M Murabito; Tetsuro Araki; Mizuki Nishino; Emelia J Benjamin; Daniel Levy; Vasan S Ramachandran; George R Washko; Jeffrey L Curtis; Christine M Freeman; Russell P Bowler; Hiroto Hatabu; George T O'Connor; Gary M Hunninghake
Journal:  Am J Respir Crit Care Med       Date:  2021-05-01       Impact factor: 30.528

Review 10.  Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis.

Authors:  Marta Bueno; Jazmin Calyeca; Mauricio Rojas; Ana L Mora
Journal:  Redox Biol       Date:  2020-03-19       Impact factor: 11.799
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.