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Literature DB >> 31008848

Deconstructing biomarkers for chronic pain: context- and hypothesis-dependent biomarker types in relation to chronic pain.

Diane Reckziegel^1,2, Etienne Vachon-Presseau¹, Bogdan Petre¹, Thomas J Schnitzer^2,3,4, Marwan N Baliki¹, A Vania Apkarian^1,2,4,5.

Abstract

This review expounds on types and properties of biomarkers for chronic pain, given a mechanistic model of processes underlying development of chronic pain. It covers advances in the field of developing biomarkers for chronic pain, while outlining the general principles of categorizing types of biomarkers driven by specific hypotheses regarding underlying mechanisms. Within this theoretical construct, example biomarkers are described and their properties expounded. We conclude that the field is advancing in important directions and the developed biomarkers have the potential of impacting both the science and the clinical practice regarding chronic pain.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Biomarkers

Year: 2019 PMID： 31008848 PMCID： PMC6478400 DOI： 10.1097/j.pain.0000000000001529

Source DB: PubMed Journal: Pain ISSN： 0304-3959 Impact factor: 6.961

68 in total

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