Literature DB >> 31007755

Traumatic optic neuropathy-a contralateral finding: A case report.

Martin Kyncl1,2, Jan Lestak1,3, Jaroslav Tintera1, Pavel Haninec4.   

Abstract

The present study demonstrates alterations of the contralateral side optic tract to an optic nerve traumatic lesion. Visual acuity of the right eye following Traumatic optic neuropathy (TON) remained at 0 following the injury. Electrophysiological examination using pattern electroretinogram revealed values reduced by 50% in the right eye compared with the left eye. Pattern visual-evoked potential evaluation indicated a bilateral lesion with a higher decrease following right eye stimulation. Magnetic resonance imaging revealed right optic nerve atrophy. Functional magnetic resonance imaging indicated decreased activity of the visual centre during left eye stimulation. The present study revealed contralateral visual tract alterations following unilateral injury, and hypothesize that the ganglion cells of the retina respond initially to glial activation. These changes are, in our view, followed by changes in the visual pathway.

Entities:  

Keywords:  electrophysiological examination; ganglion cell complex; magnetic resonance imaging; traumatic lesion of the optic nerve

Year:  2019        PMID: 31007755      PMCID: PMC6468911          DOI: 10.3892/etm.2019.7445

Source DB:  PubMed          Journal:  Exp Ther Med        ISSN: 1792-0981            Impact factor:   2.447


  2 in total

1.  Mesoscopic cortical network reorganization during recovery of optic nerve injury in GCaMP6s mice.

Authors:  Marianne Groleau; Mojtaba Nazari-Ahangarkolaee; Matthieu P Vanni; Jacqueline L Higgins; Anne-Sophie Vézina Bédard; Bernhard A Sabel; Majid H Mohajerani; Elvire Vaucher
Journal:  Sci Rep       Date:  2020-12-08       Impact factor: 4.379

Review 2.  Visually driven functional MRI techniques for characterization of optic neuropathy.

Authors:  Sujeevini Sujanthan; Amir Shmuel; Janine Dale Mendola
Journal:  Front Hum Neurosci       Date:  2022-09-09       Impact factor: 3.473

  2 in total

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