Literature DB >> 31006688

The Prevalence and Subtypes of Young Onset Dementia in Central Norway: A Population-Based Study.

Marte Kvello-Alme1,2, Geir Bråthen1,3, Linda R White1,3, Sigrid Botne Sando1,3.   

Abstract

BACKGROUND: Young onset dementia poses several challenges for the individual, health care, and society that are not normally relevant for late onset dementia, but is little researched.
OBJECTIVE: To determine the prevalence and subtypes of young onset dementia in a defined catchment area in central Norway.
METHODS: The main sources of patient identification were the databases at the Department of Neurology, University Hospital of Trondheim (St. Olav's Hospital), and Department of Psychiatry, Levanger Hospital. Both departments are the main sites for referral of young onset dementia (onset before age 65 years) in the county, covering approximately 90% of the catchment area of the study. Other sources included key persons in the communities, collaborating hospital departments examining dementia, and review of hospital records of all three hospitals in the area. Included patients met the DSM-IV criteria for dementia. The prevalence of dementias was calculated by sex and age.
RESULTS: All patients identified with dementia and onset before 65 years on census date were included in the study (n = 390). Patients younger than 65 on census date were included in the calculation of prevalence, giving a result of 76.3 per 100 000 persons at risk in the age category of 30-65 years, and 163.1 per 100,000 for the category 45-64 years. Etiology was heterogeneous, but the main subtype of dementia was Alzheimer's disease.
CONCLUSIONS: Young onset dementia affects a significant number of people in central Norway. Prevalence figures are higher than previously reported from England and Japan, but are similar to a more recent study from Australia.

Entities:  

Keywords:  Alzheimer’s disease; early onset dementia; epidemiology; prevalence

Year:  2019        PMID: 31006688      PMCID: PMC6598022          DOI: 10.3233/JAD-181223

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN: 1387-2877            Impact factor:   4.472


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