Onur Şahin1, Onur Odabaşı2, Kemal Özgür Demiralp3, Emine Şebnem Kurşun-Çakmak3, Toghrul Aliyev4. 1. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, İzmir Katip Çelebi University, İzmir, Turkey. Electronic address: onursahin43@hotmail.com. 2. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ankara Yıldırım Beyazıt University, Ankara, Turkey. 3. Department of Oral and Maxillofacial Radiology, Türkiye Public Hospitals Agency, Ministry of Health, Ankara, Turkey. 4. Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, İzmir Katip Çelebi University, İzmir, Turkey.
Abstract
OBJECTIVES: The aim of this study was to compare the panoramic radiographs of patients with early-stage and advanced-stage medication-related osteonecrosis of the jaw (MRONJ) for differences in radiographic findings and fractal dimension (FD). STUDY DESIGN: Data were collected from the medical records of 66 patients confirmed as having MRONJ. Panoramic radiographs of 66 patients (group I; without bone exposure; and group II; with bone exposure) were evaluated for the following signs; osteolysis, cortical erosion, focal and diffuse sclerosis, sequestrum, lamina dura thickening, enhancement of the inferior alveolar canal (IAC), persistent alveolar socket, pathologic fractures, and enhancement of the external oblique ridge. FD values were also compared between groups. RESULTS: The signs of focal and diffuse sclerosis, sequestrum, and enhancement of the IAC were observed significantly more often in group II than group I (P < .05). The mean FD values were 1.42 ± 0.11 in group I and 1.44 ± 0.18 in group II and were significantly different only in 1 region but not significantly different overall. CONCLUSIONS: Radiographic alterations of bone structures appeared more frequently in patients with advanced stages of MRONJ. No significant difference was detected in the FD values among the tested regions except the cancellous bone above the mandibular canal on the distal side of the mental foramen.
OBJECTIVES: The aim of this study was to compare the panoramic radiographs of patients with early-stage and advanced-stage medication-related osteonecrosis of the jaw (MRONJ) for differences in radiographic findings and fractal dimension (FD). STUDY DESIGN: Data were collected from the medical records of 66 patients confirmed as having MRONJ. Panoramic radiographs of 66 patients (group I; without bone exposure; and group II; with bone exposure) were evaluated for the following signs; osteolysis, cortical erosion, focal and diffuse sclerosis, sequestrum, lamina dura thickening, enhancement of the inferior alveolar canal (IAC), persistent alveolar socket, pathologic fractures, and enhancement of the external oblique ridge. FD values were also compared between groups. RESULTS: The signs of focal and diffuse sclerosis, sequestrum, and enhancement of the IAC were observed significantly more often in group II than group I (P < .05). The mean FD values were 1.42 ± 0.11 in group I and 1.44 ± 0.18 in group II and were significantly different only in 1 region but not significantly different overall. CONCLUSIONS: Radiographic alterations of bone structures appeared more frequently in patients with advanced stages of MRONJ. No significant difference was detected in the FD values among the tested regions except the cancellous bone above the mandibular canal on the distal side of the mental foramen.
Authors: Letícia L Quirino Pantoja; Mariana Lustosa; Paulo Márcio Yamaguti; Lídia S Rosa; André Ferreira Leite; Paulo Tadeu S Figueiredo; Luiz Claudio Castro; Ana Carolina Acevedo Journal: Calcif Tissue Int Date: 2021-10-22 Impact factor: 4.333
Authors: Catalina Moreno-Rabié; Laurence Lapauw; Hugo Gaêta-Araujo; André Ferreira-Leite; Wim Coucke; Tim van den Wyngaert; Reinhilde Jacobs Journal: Sci Rep Date: 2022-07-04 Impact factor: 4.996