Marcin Ostrowski1, Michał Marczyk2,3, Robert Dziedzic1, Małgorzata Jelitto-Górska4, Tomasz Marjański1, Sylwia Pisiak5, Tadeusz Jędrzejczyk6, Joanna Polańska2, Tomasz Zdrojewski7, Bogdan Wojtyniak8, Witold Rzyman1. 1. Department of Thoracic Surgery, Medical University of Gdańsk, Gdańsk, Poland. 2. Data Mining Division, Silesian University of Technology, Gliwice, Poland. 3. Department of Internal Medicine, Howard Hughes Medical Institute, Yale University, New Haven, CT 06519, USA. 4. Department of Radiology, Medical University of Gdańsk, Gdańsk, Poland. 5. Department of Non-Invasive Cardiac Diagnostics, Medical University of Gdańsk, Gdańsk, Poland. 6. Department of Public Health and Social Medicine, Medical University of Gdańsk, Gdańsk, Poland. 7. Department of Preventive Medicine and Education, Medical University of Gdańsk, Gdańsk, Poland. 8. National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland.
Abstract
BACKGROUND: In 2010, the World Health Organisation recommended implementation of screening programmes in four groups of diseases-neoplasms, cardiovascular diseases (CVD), diabetes mellitus (DM) and chronic obstructive pulmonary disease (COPD). It is due to the fact that they share the same, modifiable risk factors. METHODS: Between 2009 and 2011, 8637 heavy smokers (aged 50-75, smoking history >20 pack-years) were screened in the Pomeranian Pilot Lung Cancer Screening Programme (PPP) in Gdańsk, Poland. We looked at 5-year follow-up and analysed the medical events and comorbidities of all participants. One health care provider in the Polish health care system provides a unique opportunity to gather most reliable data on all medical events in each person. RESULTS: In 52.0% of lung cancer screening participants CVD (33.5%), DM (26.0%) and COPD (21.0%) were diagnosed. Prevalence of these diseases is higher in lung cancer patients than in the non-cancer screening group (P < 0.0001). One hundred and seven (1.2%) lung cancers were diagnosed during PPP programme performance and another 382 cases (4.4%) in the 5-year follow-up, so the potential mean annual lung cancer detection rate is 0.77%. CONCLUSIONS: Lung cancer screening programme offers a great potential for joint screening of lung cancer, CVD, diabetes and COPD.
BACKGROUND: In 2010, the World Health Organisation recommended implementation of screening programmes in four groups of diseases-neoplasms, cardiovascular diseases (CVD), diabetes mellitus (DM) and chronic obstructive pulmonary disease (COPD). It is due to the fact that they share the same, modifiable risk factors. METHODS: Between 2009 and 2011, 8637 heavy smokers (aged 50-75, smoking history >20 pack-years) were screened in the Pomeranian Pilot Lung Cancer Screening Programme (PPP) in Gdańsk, Poland. We looked at 5-year follow-up and analysed the medical events and comorbidities of all participants. One health care provider in the Polish health care system provides a unique opportunity to gather most reliable data on all medical events in each person. RESULTS: In 52.0% of lung cancer screening participantsCVD (33.5%), DM (26.0%) and COPD (21.0%) were diagnosed. Prevalence of these diseases is higher in lung cancerpatients than in the non-cancer screening group (P < 0.0001). One hundred and seven (1.2%) lung cancers were diagnosed during PPP programme performance and another 382 cases (4.4%) in the 5-year follow-up, so the potential mean annual lung cancer detection rate is 0.77%. CONCLUSIONS:Lung cancer screening programme offers a great potential for joint screening of lung cancer, CVD, diabetes and COPD.
Authors: Mikey B Lebrett; Haval Balata; Matthew Evison; Denis Colligan; Rebecca Duerden; Peter Elton; Melanie Greaves; John Howells; Klaus Irion; Devinda Karunaratne; Judith Lyons; Stuart Mellor; Amanda Myerscough; Tom Newton; Anna Sharman; Elaine Smith; Ben Taylor; Sarah Taylor; Anna Walsham; James Whittaker; Phil V Barber; Janet Tonge; Hilary A Robbins; Richard Booton; Philip A J Crosbie Journal: Thorax Date: 2020-07-06 Impact factor: 9.102