Claire Blanchard1, Sahar Bannani1, François Pattou2, Laurent Brunaud3, Antoine Hamy4, Niki Christou5, Muriel Mathonnet5, Marcel Dahan6, Jean-Michel Prades7, Gérard Landecy8, Henri-Pierre Dernis9, Fréderic Sebag10, Emmanuel Babin11, Alain Bizon12, Jean-Christophe Lifante13, Frank Jegoux14, Christelle Volteau15, Cécile Caillard1, Valery-Pierre Riche16, Éric Mirallié1. 1. CHU de Nantes, Clinique de Chirurgie Digestive et Endocrinienne (CCDE), Nantes Cedex 1, France. 2. CHU Lille, Université de Lille, Chirurgie Générale et Endocrinienne, Lille, France. 3. CHU Nancy - Hôpital de Brabois, Service de Chirurgie Digestive, Hépato-Biliaire, et Endocrinienne, Nancy, France. 4. CHU Angers, Chirurgie Digestive et Endocrinienne, Angers Cedex 09, France. 5. CHU de Limoges - Hôpital Dupuytren, Chirurgie Digestive, Générale et Endocrinienne, Limoges Cedex, France. 6. CHU de Toulouse - Hôpital Larrey, Chirurgie Thoracique, Pôle Voies Respiratoires, Toulouse Cedex 9, France. 7. CHU Saint-Etienne - Hôpital Nord, ORL et Chirurgie cervico-faciale et plastique, Saint-Etienne Cedex 2, France. 8. CHU de Besançon - Hôpital Jean Minjoz, Chirurgie digestive, Besançon Cedex, France. 9. Centre Hospitalier du Mans, Service ORL et chirurgie cervico-faciale, Le Mans Cedex 9, France. 10. AP-HM - Hôpital de La Timone, Chirurgie Générale, Marseille, France. 11. CHU de Caen, ORL et chirurgie cervico-faciale, Caen Cedex 9, France. 12. CHU d'Angers, ORL et chirurgie cervico-faciale, Angers Cedex 09, France. 13. Centre Hospitalier Lyon-Sud, Chirurgie Générale, Endocrinienne, Digestive et Thoracique, Pierre Bénite Cedex, France. 14. CHU de Rennes - Hôpital Pontchaillou, Service ORL et chirurgie maxillo-faciale, Rennes Cedex 9, France. 15. CHU de Nantes, DRCI, Département Promotion, Nantes Cedex 1, France. 16. Direction de Recherche clinique, Département Partenariats et Innovation, cellule Innovation, Nantes Cedex 1, France.
Abstract
BACKGROUND: The impact of obesity on total thyroidectomy (TT) morbidity (recurrent laryngeal nerve palsy and hypocalcaemia) remains largely unknown. METHODS: In a prospective study (NCT01551914), patients were divided into five groups according to their body mass index (BMI): underweight, normal weight, overweight, obese, and severely obese. Preoperative and postoperative serum calcium was measured. Recurrent laryngeal nerve (RLN) function was evaluated before discharge, and if abnormal, at 6 months. RESULTS: In total 1310 patients were included. Baseline characteristics were similar across BMI groups except for age and sex. Postoperative hypocalcaemia was more frequent in underweight compared to obese patients but the difference was not statistically significant in multivariate analysis. There was no difference between groups in terms of definitive hypocalcaemia, transient and definitive RLN palsy, and postoperative pain. CONCLUSION: Obesity does not increase intraoperative and postoperative morbidity of TT, despite a longer duration of the procedure.
BACKGROUND: The impact of obesity on total thyroidectomy (TT) morbidity (recurrent laryngeal nerve palsy and hypocalcaemia) remains largely unknown. METHODS: In a prospective study (NCT01551914), patients were divided into five groups according to their body mass index (BMI): underweight, normal weight, overweight, obese, and severely obese. Preoperative and postoperative serum calcium was measured. Recurrent laryngeal nerve (RLN) function was evaluated before discharge, and if abnormal, at 6 months. RESULTS: In total 1310 patients were included. Baseline characteristics were similar across BMI groups except for age and sex. Postoperative hypocalcaemia was more frequent in underweight compared to obesepatients but the difference was not statistically significant in multivariate analysis. There was no difference between groups in terms of definitive hypocalcaemia, transient and definitive RLN palsy, and postoperative pain. CONCLUSION:Obesity does not increase intraoperative and postoperative morbidity of TT, despite a longer duration of the procedure.