Heide Götze1, Michael Friedrich2, Sabine Taubenheim3, Andreas Dietz4, Florian Lordick5, Anja Mehnert2. 1. Department of Medical Psychology and Medical Sociology, University Medical Center Leipzig, Philipp-Rosenthal-Strasse 55, 04103, Leipzig, Germany. heide.goetze@medizin.uni-leipzig.de. 2. Department of Medical Psychology and Medical Sociology, University Medical Center Leipzig, Philipp-Rosenthal-Strasse 55, 04103, Leipzig, Germany. 3. Clinical Cancer Registry Leipzig, University Medical Center Leipzig, Leipzig, Germany. 4. Department of Otolaryngology, Head and Neck Surgery, University Medical Center Leipzig, Leipzig, Germany. 5. University Cancer Center Leipzig (UCCL), University Medical Center Leipzig, Leipzig, Germany.
Abstract
PURPOSE: Our study provides data on depression and anxiety in long-term cancer survivors, in men, women and various age groups, as well as identifies associated factors and coping-related resources. METHODS: We present data obtained from 1002 cancer survivors across a large variety of tumour entities 5 years (cohort 1) and 10 years (cohort 2) after diagnosis, in a cross-sectional study. We analysed depression (PHQ-9) and anxiety (GAD-7) symptomatology in comparison with two large age- and sex-matched samples randomly selected from the general population. RESULTS: Moderate to severe depression and anxiety were reported in 17% and 9% of cancer survivors, respectively. There were no significant differences between the 5 years and 10 years after diagnosis cohorts (p = 0.232). In both cohorts, we found higher depression and anxiety in women than in men (p < 0.001), and lower depression and anxiety in elderly patients (p < 0.001). Cancer survivors younger than 60 years of age were more depressed and anxious than the general population (p < 0.001). The variables, financial problems (Beta = 0.16, p < 0.001), global quality of life (Beta = - 0.21, p < 0.001) and cognitive function (Beta = - 0.30, p < 0.001), had the strongest association with depression and anxiety. CONCLUSIONS: For the prevention of depression and anxiety in long-term cancer survivors, individual treatment of physical and psychological symptoms is as important as social support and professional counselling. Post-treatment, cognitive limitations should be carefully assessed in long-term cancer survivorship to distinguish them from symptoms of a mental disorder, especially since younger cancer survivors of working age and female survivors seem to be more affected by depression and anxiety.
PURPOSE: Our study provides data on depression and anxiety in long-term cancer survivors, in men, women and various age groups, as well as identifies associated factors and coping-related resources. METHODS: We present data obtained from 1002 cancer survivors across a large variety of tumour entities 5 years (cohort 1) and 10 years (cohort 2) after diagnosis, in a cross-sectional study. We analysed depression (PHQ-9) and anxiety (GAD-7) symptomatology in comparison with two large age- and sex-matched samples randomly selected from the general population. RESULTS: Moderate to severe depression and anxiety were reported in 17% and 9% of cancer survivors, respectively. There were no significant differences between the 5 years and 10 years after diagnosis cohorts (p = 0.232). In both cohorts, we found higher depression and anxiety in women than in men (p < 0.001), and lower depression and anxiety in elderly patients (p < 0.001). Cancer survivors younger than 60 years of age were more depressed and anxious than the general population (p < 0.001). The variables, financial problems (Beta = 0.16, p < 0.001), global quality of life (Beta = - 0.21, p < 0.001) and cognitive function (Beta = - 0.30, p < 0.001), had the strongest association with depression and anxiety. CONCLUSIONS: For the prevention of depression and anxiety in long-term cancer survivors, individual treatment of physical and psychological symptoms is as important as social support and professional counselling. Post-treatment, cognitive limitations should be carefully assessed in long-term cancer survivorship to distinguish them from symptoms of a mental disorder, especially since younger cancer survivors of working age and female survivors seem to be more affected by depression and anxiety.
Entities:
Keywords:
Anxiety; Cancer; Depression; Health services; Quality of life
Authors: Nathan A Berger; Panos Savvides; Siran M Koroukian; Eva F Kahana; Gary T Deimling; Julia H Rose; Karen F Bowman; Robert H Miller Journal: Trans Am Clin Climatol Assoc Date: 2006
Authors: Annie M Young; Fredrick D Ashbury; Lidia Schapira; Florian Scotté; Carla I Ripamonti; Ian N Olver Journal: Support Care Cancer Date: 2020-09 Impact factor: 3.603
Authors: Daniela Doege; Melissa S Y Thong; Lena Koch-Gallenkamp; Lina Jansen; Heike Bertram; Andrea Eberle; Bernd Holleczek; Ron Pritzkuleit; Annika Waldmann; Sylke R Zeissig; Hermann Brenner; Volker Arndt Journal: Cancer Med Date: 2020-10-06 Impact factor: 4.452