| Literature DB >> 3100119 |
Y Shoenfeld, A el-Roeiy, O Ben-Yehuda, A I Pick.
Abstract
Sera from 249 patients with monoclonal gammopathies (85 multiple myeloma, 92 benign monoclonal gammopathies, 53 cryoglobulinemia, 19 Waldenström's macroglobulinemia) were examined for the presence of anti-histone activity. Thirty-four sera were found positive. In 12 of these cases the serum monoclonal immunoglobulins were purified and in all, the anti-histone activity appeared to reside in the monoclonal component. None of the patients had symptomatology of lupus despite high titers of anti-histone activity. This study demonstrates an anti-histone activity of monoclonal components of patients with monoclonal gammopathies.Entities:
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Year: 1987 PMID： 3100119 DOI： 10.1016/0090-1229(87)90012-2
Source DB: PubMed Journal: Clin Immunol Immunopathol ISSN： 0090-1229