Literature DB >> 3100000

Effect of 1 alpha-hydroxycholecalciferol on psoriasis vulgaris: a pilot study.

S Takamoto, T Onishi, S Morimoto, S Imanaka, S Yukawa, T Kozuka, Y Kitano, Y Seino, Y Kumahara.   

Abstract

We carried out a clinical trial of 1 alpha-hydroxycholecalciferol [1 alpha(OH)D3] at a dose of 1.0 microgram a day on 7 patients with psoriasis vulgaris. These patients had been treated by topical applications of corticosteroids before this study without improvement, and during the clinical trial, treatment of topical corticosteroids was continued on 6 of the 7 patients. Four of 7 patients showed complete remission and marked improvement and 2 additional patients showed minimal improvement of their skin lesions during and after the treatment with 1 alpha(OH)D3. No adverse reactions were noted during the treatment period. The mechanism of the phenomenon we observed has yet to be elucidated. Controlled trials of large numbers of patients with psoriasis vulgaris treated with 1 alpha(OH)D3 are under way.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3100000     DOI： 10.1007/bf02555172

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  24 in total

1.  Intestinal calcium absorption and serum vitamin D metabolites in normal subjects and osteoporotic patients: effect of age and dietary calcium.

Authors:  J C Gallagher; B L Riggs; J Eisman; A Hamstra; S B Arnaud; H F DeLuca
Journal:  J Clin Invest       Date:  1979-09       Impact factor: 14.808

2.  Psoriasis exacerbated by hypoparathyroidism with hypocalcaemia.

Authors:  G Risum
Journal:  Br J Dermatol       Date:  1973-09       Impact factor: 9.302

3.  Comparative proliferative kinetics of cells from normal human epidermis and benign epidermal hyperplasia (psoriasis) in vitro.

Authors:  D P Chopra; B A Flaxman
Journal:  Cell Tissue Kinet       Date:  1974-01

4.  Abnormal cell proliferation in psoriasis.

Authors:  G D Weinstein; P Frost
Journal:  J Invest Dermatol       Date:  1968-03       Impact factor: 8.551

5.  Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3.

Authors:  Z Bar-Shavit; S L Teitelbaum; P Reitsma; A Hall; L E Pegg; J Trial; A J Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  1983-10       Impact factor: 11.205

6.  Normal serum 1,25-dihydroxyvitamin D in patients with medullary carcinoma of the thyroid.

Authors:  S Lee; S Morimoto; T Onishi; M Tsuji; Y Okada; Y Seino; M Ishida; K Yamaoka; S Takai; A Miyauchi; Y Kumahara
Journal:  J Clin Endocrinol Metab       Date:  1982-08       Impact factor: 5.958

7.  Characterization of a receptor-like protein for 1,25-dihydroxyvitamin D3 in rat skin.

Authors:  R U Simpson; H F DeLuca
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205

8.  The metabolism of [6-3H]1alpha, hydroxycholecalciferol to [6-3H]1alpha,25-dihydroxycholecalciferol in a patient with renal insufficiency.

Authors:  M F Holick; M C de Blanco; M B Clark; J W Henley; R M Neer; H F DeLuca; J T Potts
Journal:  J Clin Endocrinol Metab       Date:  1977-03       Impact factor: 5.958

9.  Cultured psoriatic fibroblasts from involved and uninvolved sites have a partial but not absolute resistance to the proliferation-inhibition activity of 1,25-dihydroxyvitamin D3.

Authors:  J A MacLaughlin; W Gange; D Taylor; E Smith; M F Holick
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

10.  Measurement of circulating 1,25-dihydroxyvitamin D in man. Changes in serum concentrations during treatment with 1 alpha-hydroxycholecalciferol.

Authors:  B Lund; B Lund; O H Sørensen
Journal:  Acta Endocrinol (Copenh)       Date:  1979-06
View more
  10 in total

1.  Studies on psoriatic osteopathy.

Authors:  G Hein; K Abendroth; A Müller; G Wessel
Journal:  Clin Rheumatol       Date:  1991-03       Impact factor: 2.980

Review 2.  Diet and psoriasis, part III: role of nutritional supplements.

Authors:  Jillian W Millsop; Bhavnit K Bhatia; Maya Debbaneh; John Koo; Wilson Liao
Journal:  J Am Acad Dermatol       Date:  2014-04-26       Impact factor: 11.527

Review 3.  Dietary Intervention and Supplements in the Management of Psoriasis: Current Perspectives.

Authors:  Mimi Chung; Erin Bartholomew; Samuel Yeroushalmi; Marwa Hakimi; Tina Bhutani; Wilson Liao
Journal:  Psoriasis (Auckl)       Date:  2022-06-22

4.  Vitamin D3 inhibits proliferation and increases c-myc expression in fibroblasts from psoriatic patients.

Authors:  M Casado; M Martin; A Muñoz; J Bernal
Journal:  J Endocrinol Invest       Date:  1998-09       Impact factor: 4.256

Review 5.  Oral and Topical Vitamin D, Sunshine, and UVB Phototherapy Safely Control Psoriasis in Patients with Normal Pretreatment Serum 25-Hydroxyvitamin D Concentrations: A Literature Review and Discussion of Health Implications.

Authors:  Patrick J McCullough; William P McCullough; Douglas Lehrer; Jeffrey B Travers; Steven J Repas
Journal:  Nutrients       Date:  2021-04-29       Impact factor: 5.717

6.  Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritis.

Authors:  Susana Cubillos; Nadine Krieg; Johannes Norgauer
Journal:  PLoS One       Date:  2016-04-06       Impact factor: 3.240

7.  Dietary Behaviors in Psoriasis: Patient-Reported Outcomes from a U.S. National Survey.

Authors:  Ladan Afifi; Melissa J Danesh; Kristina M Lee; Kevin Beroukhim; Benjamin Farahnik; Richard S Ahn; Di Yan; Rasnik K Singh; Mio Nakamura; John Koo; Wilson Liao
Journal:  Dermatol Ther (Heidelb)       Date:  2017-05-19

8.  The Clinical Effect of Oral Vitamin D2 Supplementation on Psoriasis: A Double-Blind, Randomized, Placebo-Controlled Study.

Authors:  Wareeporn Disphanurat; Wongsiya Viarasilpa; Panlop Chakkavittumrong; Padcha Pongcharoen
Journal:  Dermatol Res Pract       Date:  2019-04-18

Review 9.  Oral Vitamin D Therapy in Patients with Psoriasis.

Authors:  Ana Maria Alexandra Stanescu; Anca Angela Simionescu; Camelia Cristina Diaconu
Journal:  Nutrients       Date:  2021-01-06       Impact factor: 5.717

Review 10.  Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy.

Authors:  Anna A Brożyna; Radomir M Slominski; Bogusław Nedoszytko; Michal A Zmijewski; Andrzej T Slominski
Journal:  Int J Mol Sci       Date:  2022-08-02       Impact factor: 6.208
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.