Literature DB >> 30998529

The Panacea of Human Aging: Calorie Restriction Versus Exercise.

Nicholas T Broskey1, Kara L Marlatt1, Jasper Most1, Melissa L Erickson1, Brian A Irving1,2, Leanne M Redman1.   

Abstract

Primary aging is the progressive decline in health and fitness and depends on metabolic rate and oxidative stress. Untoward changes in body composition and metabolic function characterize secondary aging. We hypothesize that both exercise and calorie restriction (CR) improve secondary aging, but only CR improves primary. However, CR followed with exercise is a superior strategy to maintain overall health and quality of life with age.

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Year:  2019        PMID: 30998529      PMCID: PMC6579613          DOI: 10.1249/JES.0000000000000193

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN: 0091-6331            Impact factor:   6.230


  50 in total

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6.  Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75.

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7.  Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial.

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9.  Regulation of aging and age-related disease by DAF-16 and heat-shock factor.

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