Literature DB >> 30996548

Comparative Study Between Oral Lorazepam and Diazepam as Sedation in Oral and Maxillofacial Surgery.

Vikas Sharma1,2, Amaninder Singh1, Parul Sharma1, Simranjeet Kaur3, Akanksha Zutshi1.   

Abstract

PURPOSE: The aim of the study was to compare the efficacy of oral lorazepam as night sedation and premedication with diazepam.
METHODS: A prospective, randomized, and double-blind study was done in 50 healthy patients in each drug group. The impacted third molar impaction was taken as the study model. Study was carried out after giving bioequivalent doses of respective drugs for either side. All the patients were assessed for quality of sleep, sedation, recall of visual stimuli, cooperation shown by patient and recovery postoperatively.
RESULTS: The study concluded that lorazepam showed more advantages than diazepam as well as patient's preference and satisfaction. However, postoperative recovery with lorazepam was longer than diazepam.

Entities:  

Keywords:  Diazepam; Lorazepam; Premedication; Sedation

Year:  2018        PMID: 30996548      PMCID: PMC6441416          DOI: 10.1007/s12663-018-1096-1

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  16 in total

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Authors:  D H Long; R J Eltringham
Journal:  Anaesthesia       Date:  1977 Jul-Aug       Impact factor: 6.955

2.  Dexmedetomidine versus midazolam in outpatient third molar surgery.

Authors:  Yakup Ustün; Murat Gündüz; Ozgür Erdoğan; M Emre Benlidayi
Journal:  J Oral Maxillofac Surg       Date:  2006-09       Impact factor: 1.895

3.  Remifentanil for use during conscious sedation in outpatient oral surgery.

Authors:  Steven Ganzberg; Richard A Pape; F Michael Beck
Journal:  J Oral Maxillofac Surg       Date:  2002-03       Impact factor: 1.895

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Authors:  N J Paymaster
Journal:  Curr Med Res Opin       Date:  1973       Impact factor: 2.580

5.  A comparison of lorazepam and diazepam as oral premedicants for surgery under regional anaesthesia.

Authors:  J A Magbagbeola
Journal:  Br J Anaesth       Date:  1974-06       Impact factor: 9.166

6.  Comparative study of two long-acting tranquillizers for oral premedication.

Authors:  M E Dodson; R J Eastley
Journal:  Br J Anaesth       Date:  1978-10       Impact factor: 9.166

7.  Premedication with lorazepam for bronchoscopy under general anaesthesia.

Authors:  J M Hewitt; A M Barr
Journal:  Br J Anaesth       Date:  1978-11       Impact factor: 9.166

8.  Lorazepam (WY 4036) as a pre-operative medication.

Authors:  N J Paymaster
Journal:  Anaesthesia       Date:  1973-09       Impact factor: 6.955

9.  Intravenous sedation for ocular surgery under local anaesthesia.

Authors:  J F Salmon; B Mets; M F James; A D Murray
Journal:  Br J Ophthalmol       Date:  1992-10       Impact factor: 4.638

10.  The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research.

Authors:  D J Buysse; C F Reynolds; T H Monk; S R Berman; D J Kupfer
Journal:  Psychiatry Res       Date:  1989-05       Impact factor: 3.222

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