Literature DB >> 30996538

Management of Odontogenic Fascial Space Infection in Hemophilia Patients: A Proposed Protocol.

Md Kalim Ansari1, Ghulam Sarwar Hashmi1, Syed Saeed Ahmed1, Sajjad Abdur Rahman1, Tabishur Rahman1.   

Abstract

PURPOSE: The purpose of this study was to suggest a protocol for the management of odontogenic space infections in patients with hemophilia which is often incompletely addressed by clinicians because of the fear of excessive bleeding leading to prolonged morbidity. METHODS AND
RESULTS: Six diagnosed cases of hemophilia (four cases of hemophilia A and two cases of hemophilia B) with odontogenic fascial space infection were included in the study. Apart from routine investigations, assessments were also done to identify inhibitors to factor VIII/IX. Factor VIII/IX was replaced along with infusion of factor eight inhibitor bypass activity (FEIBA) one hour before incision and drainage. All the cases were treated by incision and drainage along with removal of foci under local anesthesia. The postoperative outcome was uneventful in all cases except one in which postoperative bleeding was noted from the extraction site on the third day which was again managed following the designed protocol.
CONCLUSION: Maintaining good oral hygiene and seeking early dental care are of prime importance in patients with hemophilia to avoid invasive procedures. However, if odontogenic infection develops in these patients, performing timely incision and drainage using our protocol will minimize the complications and give successful outcome.

Entities:  

Keywords:  Factor VIII and IX; Fascial space infection; Gelatin sponge; Hemophilia; Third molar extraction

Year:  2018        PMID: 30996538      PMCID: PMC6441428          DOI: 10.1007/s12663-018-1117-0

Source DB:  PubMed          Journal:  J Maxillofac Oral Surg        ISSN: 0972-8270


  12 in total

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Authors:  M Stubbs; J Lloyd
Journal:  Aust Dent J       Date:  2001-03       Impact factor: 2.291

Review 2.  Treatment of factor VIII inhibitors.

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Journal:  Haemophilia       Date:  1995-01       Impact factor: 4.287

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Review 5.  Current management of hemophilia B: recommendations, complications and emerging issues.

Authors:  Massimo Franchini
Journal:  Expert Rev Hematol       Date:  2014-08-12       Impact factor: 2.929

6.  Dental surgical management of the patient with hemophilia.

Authors:  Amana Farrkh; Emilia Garrison; James J Closmann
Journal:  Gen Dent       Date:  2016 Jul-Aug

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Authors:  Y Sultan
Journal:  Thromb Haemost       Date:  1992-06-01       Impact factor: 5.249

Review 8.  Special care dentistry: part 1. Dental management of patients with inherited bleeding disorders.

Authors:  Sobia Rafique; Janice Fiske; Guy Palmer; Blanaid Daly
Journal:  Dent Update       Date:  2013-10

9.  "Antihemophilic factor is not the only answer for all factor VIII deficiencies." Case report of odontogenic infection in a patient with hemophilia A, complicated by factor VIII inhibitors, and managed by transfusion of antihemophilic factor and factor VIII inhibitor bypass activity.

Authors:  K M Sudheesh; K S N Siva Bharani; H Y Kiran; Suresh Hanagavadi
Journal:  Indian J Dent       Date:  2016-09

10.  Odontogenic infections: Microbiology and management.

Authors:  Rashi Bahl; Sumeet Sandhu; Kanwardeep Singh; Nilanchal Sahai; Mohita Gupta
Journal:  Contemp Clin Dent       Date:  2014-07
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