| Literature DB >> 30995494 |
Michael L Dustin1, Emmanuel Scotet2, Daniel Olive3.
Abstract
Invariant Vγ9Vδ2 T cells respond to "phosphoantigen" metabolites through binding to the B30.2 domain of butyrophilin BTN3A. Yang et al. (2019) use molecular dynamic simulations based on X-ray structures of distinct B30.2 domain dimers to identify the asymmetric dimer as most active, which has implications for the inside-out signaling mechanism.Mesh：
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Year: 2019 PMID： 30995494 DOI： 10.1016/j.immuni.2019.03.015
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745