Isabelle Isa Kristin Steineck1,2,3, Zeinab Mahmoudi2,4, Ajenthen Ranjan1,2,3,5, Signe Schmidt1,2,3, John Bagterp Jørgensen4, Kirsten Nørgaard1,3. 1. 1 Department of Endocrinology, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark. 2. 2 Danish Diabetes Academy, Odense, Denmark. 3. 4 Steno Diabetes Center Copenhagen, Gentofte, Denmark. 4. 3 Department of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark. 5. 5 Department of Pediatrics, Herlev University Hospital, Herlev, Denmark.
Abstract
Background: The aim was to compare the accuracy of the Dexcom® G4 Platinum continuous glucose monitor (CGM) sensor inserted on the upper arm and the abdomen in adults. Methods: Fourteen adults with type 1 diabetes wore two CGMs, one placed on the upper arm and one placed on the abdomen. Three in-clinic visits of 5 h with YSI (2300 STAT, Yellow Springs Instrument) measurements as comparator were performed. Each visit was followed by 4 days with seven-point self-monitoring of blood glucose (SMBG) in free-living conditions. Accuracy analyses on the paired CGM-YSI and CGM-SMBG measurements of the two CGM sensors were performed. Results: Using YSI as comparator, the overall Mean Absolute Relative Difference (MARD) for the CGMabd was 12.3% and CGMarm was 12.0%. The percentage of the CGM measurements in zone A of Clarke error grid analysis for the CGMabd was 85.6% and CGMarm was 86.0%. The hypoglycemia sensitivity for the CGMabd and CGMarm was 69.3%. Using SMBG as comparator, the overall MARD for the CGMabd was 12.5% and CGMarm was 12.0%. The percentage of the CGM measurements in zone A for the CGMabd was 84.1% and the CGMarm was 85.0%. The hypoglycemia sensitivity for the CGMabd was 60.0% and the CGMarm was 71.1%. All the P-values from the comparisons between the accuracy of CGMabd and CGMarm were >0.05. Conclusion: The accuracy of a Dexcom G4 Platinum CGM sensor placed on the upper arm was not different from the accuracy of the sensor placed on the abdomen in adults with type 1 diabetes.
Background: The aim was to compare the accuracy of the Dexcom® G4 Platinumcontinuous glucose monitor (CGM) sensor inserted on the upper arm and the abdomen in adults. Methods: Fourteen adults with type 1 diabetes wore two CGMs, one placed on the upper arm and one placed on the abdomen. Three in-clinic visits of 5 h with YSI (2300 STAT, Yellow Springs Instrument) measurements as comparator were performed. Each visit was followed by 4 days with seven-point self-monitoring of blood glucose (SMBG) in free-living conditions. Accuracy analyses on the paired CGM-YSI and CGM-SMBG measurements of the two CGM sensors were performed. Results: Using YSI as comparator, the overall Mean Absolute Relative Difference (MARD) for the CGMabd was 12.3% and CGMarm was 12.0%. The percentage of the CGM measurements in zone A of Clarke error grid analysis for the CGMabd was 85.6% and CGMarm was 86.0%. The hypoglycemia sensitivity for the CGMabd and CGMarm was 69.3%. Using SMBG as comparator, the overall MARD for the CGMabd was 12.5% and CGMarm was 12.0%. The percentage of the CGM measurements in zone A for the CGMabd was 84.1% and the CGMarm was 85.0%. The hypoglycemia sensitivity for the CGMabd was 60.0% and the CGMarm was 71.1%. All the P-values from the comparisons between the accuracy of CGMabd and CGMarm were >0.05. Conclusion: The accuracy of a Dexcom G4 Platinum CGM sensor placed on the upper arm was not different from the accuracy of the sensor placed on the abdomen in adults with type 1 diabetes.
Authors: Satish K Garg; Mark Kipnes; Kristin Castorino; Timothy S Bailey; Halis Kaan Akturk; John B Welsh; Mark P Christiansen; Andrew K Balo; Sue A Brown; Jennifer L Reid; Stayce E Beck Journal: Diabetes Technol Ther Date: 2022-02-21 Impact factor: 7.337
Authors: Othmar Moser; Michael C Riddell; Max L Eckstein; Peter Adolfsson; Rémi Rabasa-Lhoret; Louisa van den Boom; Pieter Gillard; Kirsten Nørgaard; Nick S Oliver; Dessi P Zaharieva; Tadej Battelino; Carine de Beaufort; Richard M Bergenstal; Bruce Buckingham; Eda Cengiz; Asma Deeb; Tim Heise; Simon Heller; Aaron J Kowalski; Lalantha Leelarathna; Chantal Mathieu; Christoph Stettler; Martin Tauschmann; Hood Thabit; Emma G Wilmot; Harald Sourij; Carmel E Smart; Peter G Jacobs; Richard M Bracken; Julia K Mader Journal: Pediatr Diabetes Date: 2020-10-13 Impact factor: 4.866
Authors: Jordi Merino; Inbar Linenberg; Kate M Bermingham; Sajaysurya Ganesh; Elco Bakker; Linda M Delahanty; Andrew T Chan; Joan Capdevila Pujol; Jonathan Wolf; Haya Al Khatib; Paul W Franks; Tim D Spector; Jose M Ordovas; Sarah E Berry; Ana M Valdes Journal: Am J Clin Nutr Date: 2022-06-07 Impact factor: 8.472