Literature DB >> 30994348

Clavukoellians A-F, Highly Rearranged Nardosinane Sesquiterpenoids with Antiangiogenic Activity from Clavularia koellikeri.

Qi Wang1,2, Zhenquan Hu1, Xiangchao Luo3, Jing Liu1, Guoqiang Li3, Shugeng Cao4, Qingsong Liu1,5.   

Abstract

Six new nardosinane-type sesquiterpenoids, clavukoellians A-F (1-6), together with one new neolemnane-type sesquiterpene, 4- O-deacetylparalemnolin D (7), were isolated from the marine soft coral Clavularia koellikeri. The structures of compounds 1-7 were elucidated by NMR spectroscopy, ECD analysis, and quantum chemical calculation methods. Compounds 1 and 7 demonstrated significant antiangiogenic activities in wound healing assays on HUVECs.

Entities:  

Year:  2019        PMID： 30994348     DOI： 10.1021/acs.jnatprod.9b00100

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  5 in total

1.  Tryptoquivalines W and X, two new compounds from a Hawaiian fungal strain and their biological activities.

Authors:  Kh Ahammad Uz Zaman; Zhenquan Hu; Xiaohua Wu; Shugeng Cao
Journal:  Tetrahedron Lett       Date:  2020-02-11       Impact factor: 2.415

2.  Antibacterial kaneoheoic acids A-F from a Hawaiian fungus Fusarium sp. FM701.

Authors:  Kh Ahammad Uz Zaman; Xiaohua Wu; Zhenquan Hu; Wesley Yoshida; Shaobin Hou; Jennifer Saito; Kristiana Alexes Avad; Kirk E Hevener; John N Alumasa; Shugeng Cao
Journal:  Phytochemistry       Date:  2020-11-17       Impact factor: 4.072

Review 3.  Natural Nitrogenous Sesquiterpenoids and Their Bioactivity: A Review.

Authors:  De-Li Chen; Bo-Wen Wang; Zhao-Cui Sun; Jun-Shan Yang; Xu-Dong Xu; Guo-Xu Ma
Journal:  Molecules       Date:  2020-05-27       Impact factor: 4.411

Review 4.  Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates.

Authors:  Claudio Luparello; Manuela Mauro; Valentina Lazzara; Mirella Vazzana
Journal:  Molecules       Date:  2020-05-26       Impact factor: 4.411

5.  Clavukoellians G-K, New Nardosinane and Aristolane Sesquiterpenoids with Angiogenesis Promoting Activity from the Marine Soft Coral Lemnalia sp.

Authors:  Qi Wang; Xuli Tang; Hui Liu; Xiangchao Luo; Ping Jyun Sung; Pinglin Li; Guoqiang Li
Journal:  Mar Drugs       Date:  2020-03-20       Impact factor: 5.118
  5 in total

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