Literature DB >> 30988575

Immune Thrombocytopenia is Still the Commonest Diagnosis on Consultative Hematology.

Ram V Nampoothiri1, Charanpreet Singh1, Deepesh Lad1, Gaurav Prakash1, Alka Khadwal1, Neelam Varma2, Pankaj Malhotra1.   

Abstract

Thrombocytopenia is often a source of concern for physicians and patients alike and is one of the commonest reasons for a hematology consultation. Through this study, we wish to ascertain the different etiologies which should be kept in mind by a hematologist when a consultation for thrombocytopenia is sought. We assessed the etiology & clinical features of thrombocytopenia seen on consultative hematology calls for patients admitted in the general ward of a tertiary care hospital. 88/277 hematology consultations taken over a course of 2 months were for thrombocytopenia. The median age of these patients was 30 years, 62.5% were female, and median platelet of 40,500/µL (1000-112000). Mild, moderate & severe thrombocytopenia was seen in 6.8%, 27.3% and 65.9% respectively. 50% of patients had a primary hematological diagnosis. Immune thrombocytopenia (ITP) was the commonest diagnosis (38.6%). Bleeding manifestations were present in 48.9% patients with 20.5% having a major bleed. One third of hematology consultations in the general ward and emergency of a tertiary care hospital are for thrombocytopenia. Almost in half, the etiology of thrombocytopenia is related to a primary hematological disorder. This information should help in decision making of use of appropriate resources.

Entities:  

Keywords:  Bleeding manifestations; Consultative hematology; Immune thrombocytopenia; Thrombocytopenia

Year:  2018        PMID: 30988575      PMCID: PMC6439238          DOI: 10.1007/s12288-018-1045-7

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN: 0971-4502            Impact factor:   0.900


  9 in total

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Journal:  Thromb Haemost       Date:  2001-11       Impact factor: 5.249

Review 2.  The frequency and clinical significance of thrombocytopenia complicating critical illness: a systematic review.

Authors:  Phil Hui; Deborah J Cook; Wendy Lim; Graeme A Fraser; Donald M Arnold
Journal:  Chest       Date:  2010-11-11       Impact factor: 9.410

Review 3.  Recommendations for the transfusion of plasma and platelets.

Authors:  Giancarlo Liumbruno; Francesco Bennardello; Angela Lattanzio; Pierluigi Piccoli; Gina Rossetti
Journal:  Blood Transfus       Date:  2009-04       Impact factor: 3.443

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Authors:  C P Teo; Y K Kueh
Journal:  Ann Acad Med Singapore       Date:  1989-07       Impact factor: 2.473

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Authors:  Lise J Estcourt; Janet Birchall; Shubha Allard; Stephen J Bassey; Peter Hersey; Jonathan Paul Kerr; Andrew D Mumford; Simon J Stanworth; Hazel Tinegate
Journal:  Br J Haematol       Date:  2016-12-23       Impact factor: 6.998

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Journal:  S Afr Med J       Date:  2015-03

7.  Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients.

Authors:  S Schulman; C Kearon
Journal:  J Thromb Haemost       Date:  2005-04       Impact factor: 5.824

8.  Etiology and complications of thrombocytopenia in hospitalized medical patients.

Authors:  Eric M Fountain; Gowthami M Arepally
Journal:  J Thromb Thrombolysis       Date:  2017-05       Impact factor: 2.300

9.  Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes.

Authors:  David R Williamson; Martin Albert; Diane Heels-Ansdell; Donald M Arnold; François Lauzier; Ryan Zarychanski; Mark Crowther; Theodore E Warkentin; Peter Dodek; John Cade; Olivier Lesur; Wendy Lim; Robert Fowler; Francois Lamontagne; Stephan Langevin; Andreas Freitag; John Muscedere; Jan O Friedrich; William Geerts; Lisa Burry; Jamal Alhashemi; Deborah Cook
Journal:  Chest       Date:  2013-10       Impact factor: 9.410

  9 in total
  1 in total

1.  A Retrospective Analysis of the Treatment Approach to Immune Thrombocytopenia in the Real World.

Authors:  Diana M Cuervo; Leonardo Enciso
Journal:  Cureus       Date:  2019-10-11
  1 in total

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